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Medicines 2018, 5(1), 10; https://doi.org/10.3390/medicines5010010

Auricular Neuromodulation: The Emerging Concept beyond the Stimulation of Vagus and Trigeminal Nerves

1
Department of Biomedical Sciences, University of Sassari, Sassari 07100, Italy
2
Head of Scientific Auriculotherapy Diploma, Faculty of Medicine, University of Paris-Saclay, Saclay 94270, France
These authors contributed equally to this work.
*
Author to whom correspondence should be addressed.
Received: 19 December 2017 / Revised: 12 January 2018 / Accepted: 19 January 2018 / Published: 21 January 2018
(This article belongs to the Special Issue Auricular Medicine: Gateway to the Brain in Healing)
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Abstract

Neuromodulation, thanks to intrinsic and extrinsic brain feedback loops, seems to be the best way to exploit brain plasticity for therapeutic purposes. In the past years, there has been tremendous advances in the field of non-pharmacological modulation of brain activity. This review of different neurostimulation techniques will focus on sites and mechanisms of both transcutaneous vagus and trigeminal nerve stimulation. These methods are scientifically validated non-invasive bottom-up brain modulation techniques, easily implemented from the outer ear. In the light of this, auricles could transpire to be the most affordable target for non-invasive manipulation of central nervous system functions. View Full-Text
Keywords: neuromodulation; vagus nerve; trigeminal nerve; auricle; auriculotherapy; auricular acupoint; peripheral neuromodulation neuromodulation; vagus nerve; trigeminal nerve; auricle; auriculotherapy; auricular acupoint; peripheral neuromodulation
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
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Mercante, B.; Deriu, F.; Rangon, C.-M. Auricular Neuromodulation: The Emerging Concept beyond the Stimulation of Vagus and Trigeminal Nerves. Medicines 2018, 5, 10.

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