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Children 2016, 3(1), 1;

Learning Lessons from Adverse Drug Reactions in Children

University of Nottingham, Division of Medical Sciences and Graduate Entry Medicine, Derbyshire Children’s Hospital, Derby DE22 3DT, UK
Author to whom correspondence should be addressed.
Academic Editor: Sari Acra
Received: 25 November 2015 / Revised: 17 December 2015 / Accepted: 18 December 2015 / Published: 8 January 2016
Full-Text   |   PDF [175 KB, uploaded 8 January 2016]


Drug toxicity is, unfortunately, a significant problem in children both in the hospital and in the community. Drug toxicity in children is different to that seen in adults. At least one in 500 children will experience an adverse drug reaction each year. For children in hospital, the risk is far greater (one in ten). Additionally, different and sometimes unique adverse drug reactions are seen in the paediatric age groups. Some of the major cases of drug toxicity historically have occurred in neonates. It is important that we understand the mechanism of action of adverse drug reactions. Greater understanding alongside rational prescribing should hopefully reduce drug toxicity in children in the future. View Full-Text
Keywords: drug toxicity; children; drug metabolism; rational drug use drug toxicity; children; drug metabolism; rational drug use
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Sammons, H.M.; Choonara, I. Learning Lessons from Adverse Drug Reactions in Children. Children 2016, 3, 1.

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