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Healthcare 2017, 5(2), 21; doi:10.3390/healthcare5020021

Irritable Bowel Syndrome: Clinical Manifestations, Dietary Influences, and Management

1
Department of Biomedical Sciences, Cooper Medical School of Rowan University, Camden, NJ 08103, USA
2
Department of Medicine, Gastroenterology/Liver Diseases Division, Cooper Medical School of Rowan University, Camden, NJ 08103, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Sampath Parthasarathy
Received: 23 December 2016 / Revised: 25 March 2017 / Accepted: 18 April 2017 / Published: 26 April 2017
View Full-Text   |   Download PDF [389 KB, uploaded 26 April 2017]   |  

Abstract

Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder that is characterized by symptoms of chronic abdominal pain and altered bowel habits in the absence of an overtly identifiable cause. It is the most commonly diagnosed functional gastrointestinal disorder, accounting for about one third of gastroenterology visits. It generally presents as a complex of symptoms, including psychological dysfunction. Hypersensitivity to certain foods, especially foods that contain high amounts of fructose, plays a role in the pathophysiology of IBS. Elevated consumption of high-fructose corn syrup (HFCS) has been discussed in this aspect. The treatment options for IBS are challenging and varied. In addition to dietary restrictions for HFCS-induced IBS, such as low-FODMAP (Fermentable Oligosaccharides, Disaccharide, Monosaccharides, and Polyols) diets, existing drug therapies are administered based on the predominant symptoms and IBS-subtype. Patients with IBS are likely to suffer from issues, such as anxiety, depression, and post-traumatic-stress disorder. Biopsychosocial factors particularly socioeconomic status, sex, and race should, thus, be considered for diagnostic evaluation of patients with IBS. View Full-Text
Keywords: irritable bowel syndrome (IBS); fructose; high-fructose corn syrup (HFCS); functional gastrointestinal disorder irritable bowel syndrome (IBS); fructose; high-fructose corn syrup (HFCS); functional gastrointestinal disorder
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Ikechi, R.; Fischer, B.D.; DeSipio, J.; Phadtare, S. Irritable Bowel Syndrome: Clinical Manifestations, Dietary Influences, and Management. Healthcare 2017, 5, 21.

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