Next Article in Journal
Dissolution Improvement of Atorvastatin Calcium using Modified Locust Bean Gum by the Solid Dispersion Technique
Previous Article in Journal
Increased 5-HT Levels Following Repeated Administration of Nigella sativa L. (Black Seed) Oil Produce Antidepressant Effects in Rats
Article Menu

Article Versions

Export Article

Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2015). Articles in this Volume were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence. Articles are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
Open AccessShort Communication
Sci. Pharm. 2014, 82(1), 171-176; doi:10.3797/scipharm.1307-08 (registering DOI)

HPLC Analysis and Cytotoxicity of n-Butanol Extract from Glyphaea brevis Roots Against C6 Glioma Cells

1
Laboratoire de Chimie Bioorganique et de Substances Naturelles (LCBOSN), UFR-SFA, Université Nangui Abrogoua, 02 BP 801 Abidjan 02, Côte d’Ivoire
2
UMR 5253, ICG Montpellier, Equipe AM2N, ENSCM, 8, rue de l'Ecole Normale, 34296 Montpellier cedex 5, France
3
INSERM U-1051, Institut des Neurosciences de Montpellier, 80 rue Augustin Fliche 34091 Montpellier, France
*
Author to whom correspondence should be addressed.
Received: 9 July 2013 / Accepted: 19 November 2013 / Published: 19 November 2013
Download PDF [136 KB, uploaded 27 September 2016]

Abstract

The n-butanol extract of the roots of Glyphaea brevis was analysed. HPLC analysis suggested the presence of phenolic compounds like protocatechuic acid (PCA). The extract showed moderate cytotoxic activity against C6 glioma cells (EC50 > 1 mg/ml).
Keywords: Glyphaea brevis; HPLC; Protocatechuic acid; Cytotoxicity; C6 Cells Glyphaea brevis; HPLC; Protocatechuic acid; Cytotoxicity; C6 Cells
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

KONAN, K.M.; MAMYRBEKOVA-BEKRO, J.A.; BAKALARA, N.; VIRIEUX, D.; PIRAT, J.-L.; BEKRO, Y.-A. HPLC Analysis and Cytotoxicity of n-Butanol Extract from Glyphaea brevis Roots Against C6 Glioma Cells. Sci. Pharm. 2014, 82, 171-176.

Show more citation formats Show less citations formats

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Sci. Pharm. EISSN 2218-0532 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top