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Sci. Pharm. 2014, 82(1), 171-176; doi:10.3797/scipharm.1307-08

HPLC Analysis and Cytotoxicity of n-Butanol Extract from Glyphaea brevis Roots Against C6 Glioma Cells

1
Laboratoire de Chimie Bioorganique et de Substances Naturelles (LCBOSN), UFR-SFA, Université Nangui Abrogoua, 02 BP 801 Abidjan 02, Côte d’Ivoire
2
UMR 5253, ICG Montpellier, Equipe AM2N, ENSCM, 8, rue de l'Ecole Normale, 34296 Montpellier cedex 5, France
3
INSERM U-1051, Institut des Neurosciences de Montpellier, 80 rue Augustin Fliche 34091 Montpellier, France
*
Author to whom correspondence should be addressed.
Received: 9 July 2013 / Accepted: 19 November 2013 / Published: 19 November 2013
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Abstract

The n-butanol extract of the roots of Glyphaea brevis was analysed. HPLC analysis suggested the presence of phenolic compounds like protocatechuic acid (PCA). The extract showed moderate cytotoxic activity against C6 glioma cells (EC50 > 1 mg/ml).
Keywords: Glyphaea brevis; HPLC; Protocatechuic acid; Cytotoxicity; C6 Cells Glyphaea brevis; HPLC; Protocatechuic acid; Cytotoxicity; C6 Cells
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

KONAN, K.M.; MAMYRBEKOVA-BEKRO, J.A.; BAKALARA, N.; VIRIEUX, D.; PIRAT, J.-L.; BEKRO, Y.-A. HPLC Analysis and Cytotoxicity of n-Butanol Extract from Glyphaea brevis Roots Against C6 Glioma Cells. Sci. Pharm. 2014, 82, 171-176.

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