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16 April 2009

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Cellulose Derivatives: Optimization of Regression Equation to Predict Viscosity of Aqueous Solutions

Department of Pharmaceutical Technology, Faculty of Pharmacy, Charles University in Prague, Heyrovského 1203, 500 05 Hradec Králové, Czech Republic

Abstract

For over 50 years, cellulose derivatives have been used as excellent pharmaceutical excipients. Commercially, cellulose products are designated with viscosity grade, proportional to the molecular weight or chain length, which identifies the product numerically based on viscosity value (in mPa⋅s) measured at 2% w/v concentration in water at 20°C using an Ubbelohde viscometer. A wide range of viscosity grades are available.

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