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Sci. Pharm. 2009, 77(Posters (PO)), 222; doi:10.3797/scipharm.oephg.21.PO-23 (registering DOI)

Design and Synthesis of 23-Amino- 24,25,26,27-tetrakisnorlanosterolacetate and Derivatives as New Antimycotic Agents

Institute of Pharmaceutical Sciences, Pharmaceutical Chemistry, Karl-Franzens-University Graz, Schubertstraße 1, A-8010 Graz
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Received: 16 April 2009 / Accepted: 16 April 2009 / Published: 16 April 2009
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Abstract

In search of new antimycotic agents acting as ergosterol biosynthesis inhibitors we investigated widely new and optimized reaction pathways for preparing different types of triazasteroids [1, 2]. The various mono-, bi-, tri- and tetracyclic triazasteroidal compounds are designed as stable aza-analogues of carbo-cationic high energy intermediates (HEIA) of fungal enzymes [1, 2].
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

GÖßNITZER, E.; PÖLZL, A.; WENDELIN, W. Design and Synthesis of 23-Amino- 24,25,26,27-tetrakisnorlanosterolacetate and Derivatives as New Antimycotic Agents. Sci. Pharm. 2009, 77, 222.

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