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Sci. Pharm. 2008, 76(4), 599-604; doi:10.3797/scipharm.0810-22 (registering DOI)

First Total Synthesis of Ergosta-5,8-dien-3β-ol Erste Totalsynthese von Ergosta-5,8-dien-3β-ol

Department Pharmazie – Zentrum für Pharmaforschung, Ludwig-Maximilians-Universität München, Butenandtstr. 5–13, 81377 München, Germany
Author to whom correspondence should be addressed.
Received: 23 October 2008 / Accepted: 12 November 2008 / Published: 13 November 2008
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The first total synthesis of ergosta-5,8-dien-3β-ol, an uncommon sterol previously isolated from an alga and several microorganisms, has been developed. For the first time, a full set of spectroscopic data of this sterol is presented.
Keywords: (3β)-Ergosta-5,8-dien-3-ol; Sterol; Hydrogenation; Birch reduction; Total synthesis (3β)-Ergosta-5,8-dien-3-ol; Sterol; Hydrogenation; Birch reduction; Total synthesis
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

GIERA, M.; BRACHER, F. First Total Synthesis of Ergosta-5,8-dien-3β-ol Erste Totalsynthese von Ergosta-5,8-dien-3β-ol. Sci. Pharm. 2008, 76, 599-604.

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