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Article

Pyrrolizidine Alkaloids in Senecio nemorensis L. from Mongolia

by
Helmut Wiedenfeld
1,*,
Narantuya S.
2,*,
Altanchimeg D.
2 and
Erhard Roeder
1
1
Pharmazeutisches Institut der Universität, An der Immenburg 4, D-53121 Bonn, Germany
2
Institute of Chemistry and Chemical Technology, Mongolian Academy of Science, Ulaanbaatar-51, Mongolia
*
Authors to whom correspondence should be addressed.
Sci. Pharm. 2000, 68(2), 207-211; https://doi.org/10.3797/scipharm.aut-00-19
Submission received: 1 March 2000 / Revised: 20 March 2000 / Accepted: 20 March 2000 / Published: 20 April 2000

Abstract

We isolated four Pyrrolizidine Alkaloids (PA) from Senecio nemorensis L. growing in Mongolia. Their structures were elucidated by spectroscopic methods to be 7-Senecioyl-9-sarracinoyl-retronecine, Retroisosenine, Doriasenine and Bulgarsenine. The alkaloidal pattern is very similar to that of the European Senecio nemorensis L., ssp. nemorensis (Rchb.) Celak. The medicinal use of this plant or of preparations from it may be hazardous to human health because of the high PA level in the plant (≈ 0.1%) and the fact that three of the PA are known to have toxic side-effects.
Keywords: Senecio nemorensis; Mongolia; Pyrrolizidine alkaloids; 7-Senecioyl-9-sarracinoylretronecine; Retroisosenine; Doriasenine; Bulgarsenine Senecio nemorensis; Mongolia; Pyrrolizidine alkaloids; 7-Senecioyl-9-sarracinoylretronecine; Retroisosenine; Doriasenine; Bulgarsenine

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MDPI and ACS Style

Wiedenfeld, H.; S., N.; D., A.; Roeder, E. Pyrrolizidine Alkaloids in Senecio nemorensis L. from Mongolia. Sci. Pharm. 2000, 68, 207-211. https://doi.org/10.3797/scipharm.aut-00-19

AMA Style

Wiedenfeld H, S. N, D. A, Roeder E. Pyrrolizidine Alkaloids in Senecio nemorensis L. from Mongolia. Scientia Pharmaceutica. 2000; 68(2):207-211. https://doi.org/10.3797/scipharm.aut-00-19

Chicago/Turabian Style

Wiedenfeld, Helmut, Narantuya S., Altanchimeg D., and Erhard Roeder. 2000. "Pyrrolizidine Alkaloids in Senecio nemorensis L. from Mongolia" Scientia Pharmaceutica 68, no. 2: 207-211. https://doi.org/10.3797/scipharm.aut-00-19

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