The Role of Oocyte Organelles in Determining Developmental Competence
AbstractThe ability of an oocyte to undergo successful cytoplasmic and nuclear maturation, fertilization and embryo development is referred to as the oocyte’s quality or developmental competence. Quality is dependent on the accumulation of organelles, metabolites and maternal RNAs during the growth and maturation of the oocyte. Various models of good and poor oocyte quality have been used to understand the essential contributors to developmental success. This review covers the current knowledge of how oocyte organelle quantity, distribution and morphology differ between good and poor quality oocytes. The models of oocyte quality are also described and their usefulness for studying the intrinsic quality of an oocyte discussed. Understanding the key critical features of cytoplasmic organelles and metabolites driving oocyte quality will lead to methods for identifying high quality oocytes and improving oocyte competence, both in vitro and in vivo. View Full-Text
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Reader, K.L.; Stanton, J.-A.L.; Juengel, J.L. The Role of Oocyte Organelles in Determining Developmental Competence. Biology 2017, 6, 35.
Reader KL, Stanton J-AL, Juengel JL. The Role of Oocyte Organelles in Determining Developmental Competence. Biology. 2017; 6(3):35.Chicago/Turabian Style
Reader, Karen L.; Stanton, Jo-Ann L.; Juengel, Jennifer L. 2017. "The Role of Oocyte Organelles in Determining Developmental Competence." Biology 6, no. 3: 35.
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