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Biology 2015, 4(3), 573-590; doi:10.3390/biology4030573

Homeostasis as the Mechanism of Evolution

Harbor-UCLA Medical Center, 1224 W. Carson Street, Torrance, CA 90502, USA
Academic Editor: Chris O’Callaghan
Received: 2 July 2015 / Revised: 11 August 2015 / Accepted: 8 September 2015 / Published: 15 September 2015
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Homeostasis is conventionally thought of merely as a synchronic (same time) servo-mechanism that maintains the status quo for organismal physiology. However, when seen from the perspective of developmental physiology, homeostasis is a robust, dynamic, intergenerational, diachronic (across-time) mechanism for the maintenance, perpetuation and modification of physiologic structure and function. The integral relationships generated by cell-cell signaling for the mechanisms of embryogenesis, physiology and repair provide the needed insight to the scale-free universality of the homeostatic principle, offering a novel opportunity for a Systems approach to Biology. Starting with the inception of life itself, with the advent of reproduction during meiosis and mitosis, moving forward both ontogenetically and phylogenetically through the evolutionary steps involved in adaptation to an ever-changing environment, Biology and Evolution Theory need no longer default to teleology. View Full-Text
Keywords: evolution; homeostasis; development; phylogeny; epigenetics; diachronic; cell-cell signaling; embryogenesis; scale-free; teleology evolution; homeostasis; development; phylogeny; epigenetics; diachronic; cell-cell signaling; embryogenesis; scale-free; teleology

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Torday, J.S. Homeostasis as the Mechanism of Evolution. Biology 2015, 4, 573-590.

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