Correction: Mahmoud et al. Neurotoxic Effect of Fipronil in Male Wistar Rats: Ameliorative Effect of L-Arginine and L-Carnitine. Biology 2021, 10, 682
by
, , and
Yasmina K. Mahmoud
1, 
Ahmed A. Ali
2,
Heba M. A. Abdelrazek
3,*,
Tahany Saleh Aldayel
4,
Mohamed M. Abdel-Daim
5
and
Menna Allah I. El-Menyawy
6 1
Department of Biochemistry, Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt
2
Hygiene, Zoonosis and Animal Behavior Department, Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt
3
Department of Physiology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt
4
Nutrition and Food Science, Department of Physical Sport Sciences, Princess Nourah Bint Abdulrahman University, Riyadh 11671, Saudi Arabia
5
Department of Pharmacology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt
6
Department of Physiology, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt
*
Author to whom correspondence should be addressed.
Biology 2023, 12(7), 904; https://doi.org/10.3390/biology12070904
Submission received: 5 May 2023
/
Revised: 9 May 2023
/
Accepted: 17 May 2023
/
Published: 25 June 2023
Figure Legend
In the original publication [1], there was a missing part in the legend for Figure 5. The correct legend appears below.
Figure 5. (A) Immunohistochemical staining of the cerebral cortex, CA region and dentate gyrus with Iba-1. Negative and non-observed immunostaining were seen in control, L-arginine (LA) and L-carnitine (LC) groups. Fipronil (FPN) group showed positive brownish Iba-1 immunoreactive microglia with numerous fine branching processes nuclei. Reduced immunoreactivity of microglia in FPN + LA and FPN + LC treated groups was seen [Anti-Iba-1 × 400]. (B) Immunoreactive parts percentage (IRP%) of Iba-1 protein expressed as mean ± SE. Symbols **, *** indicates significant p value < 0.01 and 0.001, respectively. The symbol a × b means a was statistically more varied than b; a × c means a was statistically more varied than c; and b × c means b was more statistically varied than c.
In addition, there was a mistake in the legend for Figure 6. The name of the immunohistochemical marker was mistyped as Iba-1; however, the correct one is DCX. The correct legend appears below.
Figure 6. (A) Immunohistochemical staining of the cerebral cortex, CA region and dentate gyrus with DCX. Weak perinuclear membrane reaction was seen in control, L-arginine (LA) and L-carnitine (LC) groups. The Fipronil (FPN) group showed intense positive brownish immunoreactive neurons in the subgranular and granular cell layers. Reduced immunoreactivity of microglia in FPN + LA and FPN + LC-treated groups was seen (Anti-DCX 400×). (B) Immunoreactive parts percentage (IRP%) of DCX protein expressed as mean ± SE. Symbol a × b means a was statistically more varied than b; a × c means a was statistically more varied than c; and b × c means b was statistically more varied than c. Symbols **, *** indicate significant p values < 0.01 and 0.001, respectively.
Error in Figure
In the original publication [1], there was a mistake in Figures 4 and 6 as published. Figure 4e was misdragged, and the dentate gyrus of the fipronil +L-carnitine group was misdragged in Figure 6 for DCX immunohistochemistry. The corrected Figure 4 and Figure 6 appear below.
The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.
Reference
- Mahmoud, Y.K.; Ali, A.A.; Abdelrazek, H.M.A.; Aldayel, T.S.; Abdel-Daim, M.M.; El-Menyawy, M.A.I. Neurotoxic Effect of Fipronil in Male Wistar Rats: Ameliorative Effect of L-Arginine and L-Carnitine. Biology 2021, 10, 682. [Google Scholar] [CrossRef]
Figure 4.
Dentate gyrus of control (a), L-arginine (b), L-carnitine (c) and fipronil (FPN)-treated rats (d). FPN-treated rat (d) showed shrunken, darkly stained granule cells with cytoplasmic vacuolations among few nearly normal granules cells with large vesicular nuclei. Improvements were observed in FPN + L-arginine and FPN + L-carnitine-treated groups (e,f). Stain: Hematoxylin and Eosin (H&E), magnification 400×.
Figure 4.
Dentate gyrus of control (a), L-arginine (b), L-carnitine (c) and fipronil (FPN)-treated rats (d). FPN-treated rat (d) showed shrunken, darkly stained granule cells with cytoplasmic vacuolations among few nearly normal granules cells with large vesicular nuclei. Improvements were observed in FPN + L-arginine and FPN + L-carnitine-treated groups (e,f). Stain: Hematoxylin and Eosin (H&E), magnification 400×.
Figure 6.
(A) Immunohistochemical staining of the cerebral cortex, CA region and dentate gyrus with DCX. Weak perinuclear membrane reaction was seen in control, L-arginine (LA) and L-carnitine (LC) groups. The Fipronil (FPN) group showed intense positive brownish immunoreactive neurons in the subgranular and granular cell layers. Reduced immunoreactivity of microglia in FPN + LA and FPN + LC-treated groups was seen (Anti-DCX 400×). (B) Immunoreactive parts percentage (IRP%) of DCX protein expressed as mean ± SE. Symbol a × b means a was statistically more varied than b; a × c means a was statistically more varied than c; and b × c means b was statistically more varied than c. Symbols **, *** indicate significant p values < 0.01 and 0.001, respectively.
Figure 6.
(A) Immunohistochemical staining of the cerebral cortex, CA region and dentate gyrus with DCX. Weak perinuclear membrane reaction was seen in control, L-arginine (LA) and L-carnitine (LC) groups. The Fipronil (FPN) group showed intense positive brownish immunoreactive neurons in the subgranular and granular cell layers. Reduced immunoreactivity of microglia in FPN + LA and FPN + LC-treated groups was seen (Anti-DCX 400×). (B) Immunoreactive parts percentage (IRP%) of DCX protein expressed as mean ± SE. Symbol a × b means a was statistically more varied than b; a × c means a was statistically more varied than c; and b × c means b was statistically more varied than c. Symbols **, *** indicate significant p values < 0.01 and 0.001, respectively.
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MDPI and ACS Style
Mahmoud, Y.K.; Ali, A.A.; Abdelrazek, H.M.A.; Aldayel, T.S.; Abdel-Daim, M.M.; El-Menyawy, M.A.I. Correction: Mahmoud et al. Neurotoxic Effect of Fipronil in Male Wistar Rats: Ameliorative Effect of L-Arginine and L-Carnitine. Biology 2021, 10, 682. Biology 2023, 12, 904. https://doi.org/10.3390/biology12070904
AMA Style
Mahmoud YK, Ali AA, Abdelrazek HMA, Aldayel TS, Abdel-Daim MM, El-Menyawy MAI. Correction: Mahmoud et al. Neurotoxic Effect of Fipronil in Male Wistar Rats: Ameliorative Effect of L-Arginine and L-Carnitine. Biology 2021, 10, 682. Biology. 2023; 12(7):904. https://doi.org/10.3390/biology12070904
Chicago/Turabian StyleMahmoud, Yasmina K., Ahmed A. Ali, Heba M. A. Abdelrazek, Tahany Saleh Aldayel, Mohamed M. Abdel-Daim, and Menna Allah I. El-Menyawy. 2023. "Correction: Mahmoud et al. Neurotoxic Effect of Fipronil in Male Wistar Rats: Ameliorative Effect of L-Arginine and L-Carnitine. Biology 2021, 10, 682" Biology 12, no. 7: 904. https://doi.org/10.3390/biology12070904
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