Next Article in Journal
Prolonged Corrosion Stability of a Microchip Sensor Implant during In Vivo Exposure
Next Article in Special Issue
Accuracy of Continuous Glucose Monitoring before, during, and after Aerobic and Anaerobic Exercise in Patients with Type 1 Diabetes Mellitus
Previous Article in Journal
Enzymatic Fuel Cells: Towards Self-Powered Implantable and Wearable Diagnostics
Previous Article in Special Issue
A Cuprous Oxide Thin Film Non-Enzymatic Glucose Sensor Using Differential Pulse Voltammetry and Other Voltammetry Methods and a Comparison to Different Thin Film Electrodes on the Detection of Glucose in an Alkaline Solution
Article Menu
Issue 1 (March) cover image

Export Article

Open AccessArticle
Biosensors 2018, 8(1), 12; https://doi.org/10.3390/bios8010012

Glucose Sensing Using Capacitive Biosensor Based on Polyvinylidene Fluoride Thin Film

1
Department of Physics, Faculty of Sciences and Technology, UIN Syarif Hidayatullah Jakarta, Tangerang Selatan, Banten 15412, Indonesia
2
Department of Physics, Faculty of Mathematics and Natural Sciences, Universitas Negeri Padang, Padang 25131, Indonesia
*
Author to whom correspondence should be addressed.
Received: 10 November 2017 / Revised: 24 January 2018 / Accepted: 24 January 2018 / Published: 30 January 2018
(This article belongs to the Special Issue Continuous Glucose Monitoring)
View Full-Text   |   Download PDF [2523 KB, uploaded 30 January 2018]   |  

Abstract

A polyvinylidene fluoride (PVDF) film-based capacitive biosensor was developed for glucose sensing. This device consists of a PVDF film sandwiched between two electrodes. A capacitive biosensor measures the dielectric properties of the dielectric layers at the interface between the electrolyte and the electrode. A glucose oxidase (GOx) enzyme was immobilized onto the electrode to oxidize glucose. In practice, the biochemical reaction of glucose with the GOx enzyme generates free electron carriers. Consequently, the potential difference between the electrodes is increased, resulting in a measurable voltage output of the biosensor. The device was tested for various glucose concentrations in the range of 0.013 to 5.85 M, and various GOx enzyme concentrations between 4882.8 and 2.5 million units/L. We found that the sensor output increased with increasing glucose concentration up to 5.85 M. These results indicate that the PVDF film-based capacitive biosensors can be properly applied to glucose sensing and provide opportunities for the low-cost fabrication of glucose-based biosensors based on PVDF materials. View Full-Text
Keywords: capacitive biosensor; glucose sensing; GOx enzyme; PVDF film capacitive biosensor; glucose sensing; GOx enzyme; PVDF film
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary material

SciFeed

Share & Cite This Article

MDPI and ACS Style

Hartono, A.; Sanjaya, E.; Ramli, R. Glucose Sensing Using Capacitive Biosensor Based on Polyvinylidene Fluoride Thin Film. Biosensors 2018, 8, 12.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Biosensors EISSN 2079-6374 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top