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Diagnostics 2013, 3(4), 356-371; doi:10.3390/diagnostics3040356

Functional Imaging in Diagnostic of Orthopedic Implant-Associated Infections

AO Foundation, Clavadelerstrasse 8, 7270 Davos, Switzerland
Received: 30 July 2013 / Revised: 10 September 2013 / Accepted: 22 September 2013 / Published: 21 October 2013
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Surgeries’ sterile conditions and perioperative antibiotic therapies decrease implant associated infections rates significantly. However, up to 10% of orthopedic devices still fail due to infections. An implant infection generates a high socio-economic burden. An early diagnosis of an infection would significantly improve patients’ outcomes. There are numerous clinical tests to diagnose infections. The “Gold Standard” is a microbiological culture, which requires an invasive sampling and lasts up to several weeks. None of the existing tests in clinics alone is sufficient for a conclusive diagnosis of an infection. Meanwhile, there are functional imaging modalities, which hold the promise of a non-invasive, quick, and specific infection diagnostic. This review focuses on orthopedic implant-associated infections, their pathogenicity, diagnosis and functional imaging.
Keywords: orthopedic implant associated infections; diagnostic imaging orthopedic implant associated infections; diagnostic imaging
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Potapova, I. Functional Imaging in Diagnostic of Orthopedic Implant-Associated Infections. Diagnostics 2013, 3, 356-371.

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