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Life 2014, 4(2), 174-188; doi:10.3390/life4020174
Article

Cineradiographic Analysis of Mouse Postural Response to Alteration of Gravity and Jerk (Gravity Deceleration Rate)

1
, 2
, 2,3
 and 3,*
Received: 14 January 2014; in revised form: 14 April 2014 / Accepted: 15 April 2014 / Published: 24 April 2014
(This article belongs to the Special Issue Response of Terrestrial Life to Space Conditions)
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Abstract: The ability to maintain the body relative to the external environment is important for adaptation to altered gravity. However, the physiological limits for adaptation or the disruption of body orientation are not known. In this study, we analyzed postural changes in mice upon exposure to various low gravities. Male C57BL6/J mice (n = 6) were exposed to various gravity-deceleration conditions by customized parabolic flight-maneuvers targeting the partial-gravity levels of 0.60, 0.30, 0.15 and μ g (<0.001 g). Video recordings of postural responses were analyzed frame-by-frame by high-definition cineradiography and with exact instantaneous values of gravity and jerk. As a result, the coordinated extension of the neck, spine and hindlimbs was observed during the initial phase of gravity deceleration. Joint angles widened to 120%–200% of the reference g level, and the magnitude of the thoracic-curvature stretching was correlated with gravity and jerk, i.e., the gravity deceleration rate. A certain range of jerk facilitated mouse skeletal stretching efficiently, and a jerk of −0.3~−0.4 j (g/s) induced the maximum extension of the thoracic-curvature. The postural response of animals to low gravity may undergo differential regulation by gravity and jerk.
Keywords: gravity; jerk; parabolic flight; threshold; spine; partial gravity; reflex; space; kinesiology; cineradiography gravity; jerk; parabolic flight; threshold; spine; partial gravity; reflex; space; kinesiology; cineradiography
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Hasegawa, K.; de Campos, P.S.; Zeredo, J.L.; Kumei, Y. Cineradiographic Analysis of Mouse Postural Response to Alteration of Gravity and Jerk (Gravity Deceleration Rate). Life 2014, 4, 174-188.

AMA Style

Hasegawa K, de Campos PS, Zeredo JL, Kumei Y. Cineradiographic Analysis of Mouse Postural Response to Alteration of Gravity and Jerk (Gravity Deceleration Rate). Life. 2014; 4(2):174-188.

Chicago/Turabian Style

Hasegawa, Katsuya; de Campos, Priscila S.; Zeredo, Jorge L.; Kumei, Yasuhiro. 2014. "Cineradiographic Analysis of Mouse Postural Response to Alteration of Gravity and Jerk (Gravity Deceleration Rate)." Life 4, no. 2: 174-188.

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