Next Article in Journal
Symmetry and Beauty in Plato
Next Article in Special Issue
Fluctuating Asymmetry: Methods, Theory, and Applications
Previous Article in Journal
Hartee Fock Symmetry Breaking Effects in La2CuO4: Hints for connecting the Mott and Slater Pictures and Pseudogap Prediction
Previous Article in Special Issue
Inverse Supersymmetry Breaking in S1 × R3
Symmetry 2010, 2(2), 437-454; doi:10.3390/sym2020437
Review

Diastereoselective Desymmetrization of Symmetric Dienes and its Synthetic Application

 and *
Received: 30 January 2010; in revised form: 4 March 2010 / Accepted: 4 March 2010 / Published: 25 March 2010
(This article belongs to the Special Issue Feature Papers: Symmetry Concepts and Applications)
Download PDF [180 KB, uploaded 25 March 2010]
Abstract: The desymmetrization of symmetric compounds is a useful approach to obtain chiral building blocks. Readily available precursors with a prochiral unit could be converted into complex molecules with multiple stereogenic centers in a single step. In this review, recent advances in the desymmetrization of symmetric dienes in the diastereotopic group differentiating reaction and its synthetic application are presented.
Keywords: desymmetrization; symmetric diene; chiral auxiliary; C2-symmetric diol; acetal desymmetrization; symmetric diene; chiral auxiliary; C2-symmetric diol; acetal
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Export to BibTeX |
EndNote


MDPI and ACS Style

Nakahara, K.; Fujioka, H. Diastereoselective Desymmetrization of Symmetric Dienes and its Synthetic Application. Symmetry 2010, 2, 437-454.

AMA Style

Nakahara K, Fujioka H. Diastereoselective Desymmetrization of Symmetric Dienes and its Synthetic Application. Symmetry. 2010; 2(2):437-454.

Chicago/Turabian Style

Nakahara, Kenji; Fujioka, Hiromichi. 2010. "Diastereoselective Desymmetrization of Symmetric Dienes and its Synthetic Application." Symmetry 2, no. 2: 437-454.


Symmetry EISSN 2073-8994 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert