Helicene-Based Chiral Auxiliaries and Chirogenesis
Abstract
:1. Introduction
2. Overview of Latest Reviews
3. Classification and Nomenclature
3.1. Structural Diversity
3.1.1. Carbohelicenes
3.1.2. Heterohelicenes
3.1.3. Charged Helicenes
3.1.4. Special Structural Type of Helicene-Like Molecules
3.2. Spatial Diversity
3.2.1. Chiral (Configurationally Stable) Helicenes
3.2.2. Achiral Helicenes
3.2.3. Stereodynamic Helicenes
3.2.4. Meso Helicenes
4. General Description and Main Synthetic Approaches toward Helicene-Based Chirogenic Systems
5. Helicenes as Chiral Auxiliary/Reagent or Additive
6. Helicenes as Chiral Catalysts
7. Helicene in Supramolecular Chirogenesis
7.1. Helicene-Based Chiral Recognition of Small Molecules
7.2. Polymeric Helicene-Based Chiral Recognition
7.3. Helicene-Based Chiral Recognition via Nanoparticles
7.4. Helicene-Based Chiral Recognition Involving Biologically Relevant Molecules
7.5. Helicene-Based Chiral Recognition via Self-Assembly
8. Enantiopure Helicenes: Enantioselective Synthesis, Chiral Separation, and Racemization
9. Conclusions
Acknowledgments
Conflicts of Interest
References
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(P)-53 | [(η3-C3H5)-PdCl]2 (2.5 mol%), (P)-53 (10 mol%), BSA, LiOAc, CH2Cl2, rt, 24 h | 90 | 96 | [52] |
(P)-54 | [(η3-C3H5)-PdCl]2 (2.5 mol%), (P)-54 (10 mol%), BSA, LiOAc, CH2Cl2, rt, 24 h | 97 | 99 | [52] |
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Hasan, M.; Borovkov, V. Helicene-Based Chiral Auxiliaries and Chirogenesis. Symmetry 2018, 10, 10. https://doi.org/10.3390/sym10010010
Hasan M, Borovkov V. Helicene-Based Chiral Auxiliaries and Chirogenesis. Symmetry. 2018; 10(1):10. https://doi.org/10.3390/sym10010010
Chicago/Turabian StyleHasan, Mohammed, and Victor Borovkov. 2018. "Helicene-Based Chiral Auxiliaries and Chirogenesis" Symmetry 10, no. 1: 10. https://doi.org/10.3390/sym10010010