Under Pressure: Mechanical Stress Management in the Nucleus
AbstractCells are constantly adjusting to the mechanical properties of their surroundings, operating a complex mechanochemical feedback, which hinges on mechanotransduction mechanisms. Whereas adhesion structures have been shown to play a central role in mechanotransduction, it now emerges that the nucleus may act as a mechanosensitive structure. Here, we review recent advances demonstrating that mechanical stress emanating from the cytoskeleton can activate pathways in the nucleus which eventually impact both its structure and the transcriptional machinery. View Full-Text
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Belaadi, N.; Aureille, J.; Guilluy, C. Under Pressure: Mechanical Stress Management in the Nucleus. Cells 2016, 5, 27.
Belaadi N, Aureille J, Guilluy C. Under Pressure: Mechanical Stress Management in the Nucleus. Cells. 2016; 5(2):27.Chicago/Turabian Style
Belaadi, Néjma; Aureille, Julien; Guilluy, Christophe. 2016. "Under Pressure: Mechanical Stress Management in the Nucleus." Cells 5, no. 2: 27.
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