TRP Channels in Oxidative Stress Signalling
1. Introduction
2. Ischemic Stroke Brain Damage
3. Peripheral Artery Disease
4. Atherosclerosis
5. Metabolic Syndrome
6. Diabetic Cataract
7. Cutaneous Melanoma
Author Contributions
Funding
Conflicts of Interest
References
- Nilius, B.; Szallasi, A. Transient receptor potential channels as drug targets: From the science of basic research to the art of medicine. Pharmacol. Rev. 2014, 66, 676–814. [Google Scholar] [CrossRef] [PubMed]
- Kozai, D.; Ogawa, N.; Mori, Y. Redox regulation of transient receptor potential channels. Antioxid. Redox Signal. 2014, 21, 971–986. [Google Scholar] [CrossRef] [PubMed]
- Zhang, P.; Li, W.; Liu, Y.; Gao, Y.; Abumaria, N. Neuroprotective effects of TRPM7 deletion in parvalbumin GABAergic vs. Glutamatergic neurons following ischemia. Cells 2022, 11, 1178. [Google Scholar] [CrossRef] [PubMed]
- Zong, P.; Lin, Q.; Feng, J.; Yue, L. A Systemic Review of the integral role of TRPM2 in ischemic stroke: From upstream risk factors to ultimate neuronal death. Cells 2022, 11, 491. [Google Scholar] [CrossRef] [PubMed]
- Numaga-Tomita, T.; Shimauchi, T.; Oda, S.; Tanaka, T.; Nishiyama, K.; Nishimura, A.; Birnbaumer, L.; Mori, Y.; Nishida, M. TRPC6 regulates phenotypic switching of vascular smooth muscle cells through plasma membrane potential-dependent coupling with PTEN. FASEB J. 2019, 33, 9785–9796. [Google Scholar] [CrossRef] [PubMed]
- Shimauchi, T.; Numaga-Tomita, T.; Kato, Y.; Morimoto, H.; Sakata, K.; Matsukane, R.; Nishimura, A.; Nishiyama, K.; Shibuta, A.; Horiuchi, Y.; et al. A TRPC3/6 channel inhibitor promotes arteriogenesis after hind-limb ischemia. Cells 2022, 11, 2041. [Google Scholar] [CrossRef] [PubMed]
- Zhang, Y.; Ying, F.; Tian, X.; Lei, Z.; Li, X.; Lo, C.-Y.; Li, J.; Jiang, L.; Yao, X. TRPM2 promotes atherosclerotic progression in a mouse model of atherosclerosis. Cells 2022, 11, 1423. [Google Scholar] [CrossRef] [PubMed]
- Araújo, M.C.; Soczek, S.H.S.; Pontes, J.P.; Marques, L.A.C.; Santos, G.S.; Simão, G.; Bueno, L.R.; Maria-Ferreira, D.; Muscará, M.N.; Fernandes, E.S. An overview of the TRP-oxidative stress axis in metabolic syndrome: Insights for novel therapeutic approaches. Cells 2022, 11, 1292. [Google Scholar] [CrossRef] [PubMed]
- Chen, L.; Chen, Y.; Ding, W.; Zhan, T.; Zhu, J.; Zhang, L.; Wang, H.; Shen, B.; Wang, Y. Oxidative stress-induced TRPV2 expression increase is involved in diabetic cataracts and apoptosis of lens epithelial cells in a high-glucose environment. Cells 2022, 11, 1196. [Google Scholar] [CrossRef] [PubMed]
- De Logu, F.; Souza Monteiro de Araujo, D.; Ugolini, F.; Iannone, L.F.; Vannucchi, M.; Portelli, F.; Landini, L.; Titiz, M.; De Giorgi, V.; Geppetti, P.; et al. The TRPA1 channel amplifies the oxidative stress signal in melanoma. Cells 2021, 10, 3131. [Google Scholar] [CrossRef] [PubMed]
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Jiang, L.-H.; Yao, X.; Çiğ, B. TRP Channels in Oxidative Stress Signalling. Cells 2023, 12, 1251. https://doi.org/10.3390/cells12091251
Jiang L-H, Yao X, Çiğ B. TRP Channels in Oxidative Stress Signalling. Cells. 2023; 12(9):1251. https://doi.org/10.3390/cells12091251
Chicago/Turabian StyleJiang, Lin-Hua, Xiaoqiang Yao, and Bilal Çiğ. 2023. "TRP Channels in Oxidative Stress Signalling" Cells 12, no. 9: 1251. https://doi.org/10.3390/cells12091251