Role of SHH in Patterning Human Pluripotent Cells towards Ventral Forebrain Fates
Abstract
:1. Modeling of CNS Development and Disease In Vivo and In Vitro
2. SHH Signaling during Embryogenesis
3. Cell Types Requiring SHH Signaling in Vertebrate Development and Their Role in Diseases of the CNS
4. Elucidating the SHH Signaling Pathway Paves the Way for Application in In Vitro Patterning
5. The Use of SHH in In Vitro Disease Modeling
5.1. Parkinson’s Disease
5.2. Motor Neuron Disorders
5.3. Serotonin Neurons
6. The Future of In Vitro Technology
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Brady, M.V.; Vaccarino, F.M. Role of SHH in Patterning Human Pluripotent Cells towards Ventral Forebrain Fates. Cells 2021, 10, 914. https://doi.org/10.3390/cells10040914
Brady MV, Vaccarino FM. Role of SHH in Patterning Human Pluripotent Cells towards Ventral Forebrain Fates. Cells. 2021; 10(4):914. https://doi.org/10.3390/cells10040914
Chicago/Turabian StyleBrady, Melanie V., and Flora M. Vaccarino. 2021. "Role of SHH in Patterning Human Pluripotent Cells towards Ventral Forebrain Fates" Cells 10, no. 4: 914. https://doi.org/10.3390/cells10040914