Increased X-ray Visualization of Shape Memory Polymer Foams by Chemical Incorporation of Iodine Motifs
AbstractShape memory polymers can be programmed into a secondary geometry and recovered to their primary geometry with the application of a controlled stimulus. Porous shape memory polymer foam scaffolds that respond to body temperature show particular promise for embolic medical applications. A limitation for the minimally invasive delivery of these materials is an inherent lack of X-ray contrast. In this work, a triiodobenzene containing a monomer was incorporated into a shape memory polymer foam material system to chemically impart X-ray visibility and increase material toughness. Composition and process changes enabled further control over material density and thermomechanical properties. The proposed material system demonstrates a wide range of tailorable functional properties for the design of embolic medical devices, including X-ray visibility, expansion rate, and porosity. Enhanced visualization of these materials can improve the acute performance of medical devices used to treat vascular malformations, and the material porosity provides a healing scaffold for durable occlusion. View Full-Text
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Nash, L.D.; Browning Monroe, M.B.; Ding, Y.-H.; Ezell, K.P.; Boyle, A.J.; Kadirvel, R.; Kallmes, D.F.; Maitland, D.J. Increased X-ray Visualization of Shape Memory Polymer Foams by Chemical Incorporation of Iodine Motifs. Polymers 2017, 9, 381.
Nash LD, Browning Monroe MB, Ding Y-H, Ezell KP, Boyle AJ, Kadirvel R, Kallmes DF, Maitland DJ. Increased X-ray Visualization of Shape Memory Polymer Foams by Chemical Incorporation of Iodine Motifs. Polymers. 2017; 9(8):381.Chicago/Turabian Style
Nash, Landon D.; Browning Monroe, Mary B.; Ding, Yong-Hong; Ezell, Kendal P.; Boyle, Anthony J.; Kadirvel, Ramanathan; Kallmes, David F.; Maitland, Duncan J. 2017. "Increased X-ray Visualization of Shape Memory Polymer Foams by Chemical Incorporation of Iodine Motifs." Polymers 9, no. 8: 381.