Probing the Nanoscopic Thermodynamic Fingerprint of Paramagnetic Ligands Interacting with Amphiphilic Macromolecules
AbstractSelf-assembly of macromolecules with ligands is an intricate dynamic process that depends on a wide variety of parameters and forms the basis of many essential biological processes. We elucidate the underlying energetic processes of self-assembly in a model system consisting of amphiphilic core-shell polymers interacting with paramagnetic, amphiphilic ligand molecules from temperature-dependent continuous wave electron paramagnetic resonance (CW EPR) spectroscopy subsequent to spectral simulation. The involved processes as observed from the ligands’ point of view are either based on temperature-dependent association constants (KA,j,k) or dynamic rotational regime interconversion (IC) constants (KIC,j,k). The interconversion process describes a transition from Brownian (b1) towards free (b2) diffusion of ligand. Both processes exhibit non-linear van’t Hoff (lnK vs. T−1) plots in the temperature range of liquid water and we retrieve decisive dynamic information of the system from the energetic fingerprints of ligands on the nanoscale, especially from the temperature-dependent interconversion heat capacity (∆C°P,IC). View Full-Text
- Supplementary File 1:
PDF-Document (PDF, 585 KB)
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Reichenwallner, J.; Schwieger, C.; Hinderberger, D. Probing the Nanoscopic Thermodynamic Fingerprint of Paramagnetic Ligands Interacting with Amphiphilic Macromolecules. Polymers 2017, 9, 324.
Reichenwallner J, Schwieger C, Hinderberger D. Probing the Nanoscopic Thermodynamic Fingerprint of Paramagnetic Ligands Interacting with Amphiphilic Macromolecules. Polymers. 2017; 9(8):324.Chicago/Turabian Style
Reichenwallner, Jörg; Schwieger, Christian; Hinderberger, Dariush. 2017. "Probing the Nanoscopic Thermodynamic Fingerprint of Paramagnetic Ligands Interacting with Amphiphilic Macromolecules." Polymers 9, no. 8: 324.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.