Engineering Cell Surfaces with Polyelectrolyte Materials for Translational Applications
AbstractEngineering cell surfaces with natural or synthetic materials is a unique and powerful strategy for biomedical applications. Cells exhibit more sophisticated migration, control, and functional capabilities compared to nanoparticles, scaffolds, viruses, and other engineered materials or agents commonly used in the biomedical field. Over the past decade, modification of cell surfaces with natural or synthetic materials has been studied to exploit this complexity for both fundamental and translational goals. In this review we present the existing biomedical technologies for engineering cell surfaces with one important class of materials, polyelectrolytes. We begin by introducing the challenges facing the cell surface engineering field. We then discuss the features of polyelectrolytes and how these properties can be harnessed to solve challenges in cell therapy, tissue engineering, cell-based drug delivery, sensing and tracking, and immune modulation. Throughout the review, we highlight opportunities to drive the field forward by bridging new knowledge of polyelectrolytes with existing translational challenges. View Full-Text
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Zhang, P.; Bookstaver, M.L.; Jewell, C.M. Engineering Cell Surfaces with Polyelectrolyte Materials for Translational Applications. Polymers 2017, 9, 40.
Zhang P, Bookstaver ML, Jewell CM. Engineering Cell Surfaces with Polyelectrolyte Materials for Translational Applications. Polymers. 2017; 9(2):40.Chicago/Turabian Style
Zhang, Peipei; Bookstaver, Michelle L.; Jewell, Christopher M. 2017. "Engineering Cell Surfaces with Polyelectrolyte Materials for Translational Applications." Polymers 9, no. 2: 40.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.