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Pharmaceutics 2015, 7(4), 542-553; doi:10.3390/pharmaceutics7040542

Genomic Discoveries and Personalized Medicine in Neurological Diseases

1
U.S. Food and Drug Administration, Center for Drug Evaluation and Research, 10903 New Hampshire Ave, Silver Spring, MD 20993, USA
2
U.S. Food and Drug Administration, National Center for Toxicological Research, 3900 NCTR Road, Jefferson, AR 72079, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Afzal R. Mohammed
Received: 23 September 2015 / Revised: 30 November 2015 / Accepted: 2 December 2015 / Published: 7 December 2015
(This article belongs to the Special Issue Personalized Medicine and Pharmacogenomics)
View Full-Text   |   Download PDF [1279 KB, uploaded 7 December 2015]   |  

Abstract

In the past decades, we have witnessed dramatic changes in clinical diagnoses and treatments due to the revolutions of genomics and personalized medicine. Undoubtedly we also met many challenges when we use those advanced technologies in drug discovery and development. In this review, we describe when genomic information is applied in personal healthcare in general. We illustrate some case examples of genomic discoveries and promising personalized medicine applications in the area of neurological disease particular. Available data suggest that individual genomics can be applied to better treat patients in the near future. View Full-Text
Keywords: genomics; personalized medicine; neurological disease genomics; personalized medicine; neurological disease
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Zhang, L.; Hong, H. Genomic Discoveries and Personalized Medicine in Neurological Diseases. Pharmaceutics 2015, 7, 542-553.

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