Next Article in Journal / Special Issue
The Effects of Pregnenolone 16α-Carbonitrile Dosing on Digoxin Pharmacokinetics and Intestinal Absorption in the Rat
Previous Article in Journal / Special Issue
Quantification of Process Induced Disorder in Milled Samples Using Different Analytical Techniques
Pharmaceutics 2010, 2(1), 50-60; doi:10.3390/pharmaceutics2010050
Article

Ingredient Consistency of Commercially Available Polyphenol and Tocopherol Nutraceuticals

,
 and
*
Department of Pharmaceutical Sciences, College of Pharmacy, Washington State University, Pullman, WA 99164-6534, USA
* Author to whom correspondence should be addressed.
Received: 28 January 2010 / Revised: 3 March 2010 / Accepted: 4 March 2010 / Published: 8 March 2010
(This article belongs to the Special Issue What's on Board in Pharmaceutics)
View Full-Text   |   Download PDF [107 KB, uploaded 8 March 2010]

Abstract

Label claims of vitamin E succinate and polyphenolic nutraceuticals are assessed. A validated HPLC method was utilized to assess vitamin E succinate products. Three novel LC/MS methods were used to assess the polyphenols, pterostilbene, phloretin, and myricetin, in dietary supplements. The amount of vitamin E succinate varied from 0-130% of the stated label content with two products containing vitamin E acetate rather than vitamin E succinate. Expected polyphenols were found in 7 of the 8 supplement products. None of the polyphenol supplements contained content within 100-120% of label claims. The present study indicates a lack of uniformity in nutraceutical products.
Keywords: content analysis; polyphenols; nutraceuticals; vitamin E succinate; pterostilbene; phloretin; myricetin content analysis; polyphenols; nutraceuticals; vitamin E succinate; pterostilbene; phloretin; myricetin
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
SciFeed

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote |
RIS
MDPI and ACS Style

Remsberg, C.M.; Good, R.L.; Davies, N.M. Ingredient Consistency of Commercially Available Polyphenol and Tocopherol Nutraceuticals. Pharmaceutics 2010, 2, 50-60.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here

Comments

[Return to top]
Pharmaceutics EISSN 1999-4923 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert