Chitosan Gel to Treat Pressure Ulcers: A Clinical Pilot Study
AbstractChitosan is biopolymer with promising properties in wound healing. Chronic wounds represent a significant burden to both the patient and the medical system. Among chronic wounds, pressure ulcers are one of the most common types of complex wound. The efficacy and the tolerability of chitosan gel formulation, prepared into the hospital pharmacy, in the treatment of pressure ulcers of moderate severity were evaluated. The endpoint of this phase II study was the reduction of the area of the lesion by at least 20% after four weeks of treatment. Thus, 20 adult volunteers with pressure ulcers within predetermined parameters were involved in a 30 days study. Dressing change was performed twice a week at outpatient clinic upon chronic wounds management. In the 90% of patients involved in the study, the treatment was effective, with a reduction of the area of the lesion and wound healing progress. The study demonstrated the efficacy of the gel formulation for treatment of pressure ulcers, also providing a strong reduction of patient management costs. View Full-Text
Share & Cite This Article
Campani, V.; Pagnozzi, E.; Mataro, I.; Mayol, L.; Perna, A.; D’Urso, F.; Carillo, A.; Cammarota, M.; Maiuri, M.C.; De Rosa, G. Chitosan Gel to Treat Pressure Ulcers: A Clinical Pilot Study. Pharmaceutics 2018, 10, 15.
Campani V, Pagnozzi E, Mataro I, Mayol L, Perna A, D’Urso F, Carillo A, Cammarota M, Maiuri MC, De Rosa G. Chitosan Gel to Treat Pressure Ulcers: A Clinical Pilot Study. Pharmaceutics. 2018; 10(1):15.Chicago/Turabian Style
Campani, Virginia; Pagnozzi, Eliana; Mataro, Ilaria; Mayol, Laura; Perna, Alessandra; D’Urso, Floriana; Carillo, Antonietta; Cammarota, Maria; Maiuri, Maria C.; De Rosa, Giuseppe. 2018. "Chitosan Gel to Treat Pressure Ulcers: A Clinical Pilot Study." Pharmaceutics 10, no. 1: 15.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.