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Materials 2017, 10(2), 214; doi:10.3390/ma10020214

Laser Surface Microstructuring of Biocompatible Materials Using a Microlens Array and the Talbot Effect: Evaluation of the Cell Adhesion

1
Photonics4Life Research Group, Departamento de Física Aplicada, Facultad de Física, Universidade de Santiago de Compostela, Santiago de Compostela 15782, Spain
2
Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Complexo Hospitalario Universitario de Santiago de Compostela (CHUS) SERGAS, Santiago de Compostela 15706, Spain and CIBERCV, Madrid, Spain
*
Author to whom correspondence should be addressed.
Academic Editor: Naozumi Teramoto
Received: 13 January 2017 / Revised: 14 February 2017 / Accepted: 16 February 2017 / Published: 22 February 2017
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Abstract

A laser based technique for microstructuring titanium and tantalum substrates using the Talbot effect and an array of microlenses is presented. By using this hybrid technique; we are able to generate different patterns and geometries on the top surfaces of the biomaterials. The Talbot effect allows us to rapidly make microstructuring, solving the common problems of using microlenses for multipatterning; where the material expelled during the ablation of biomaterials damages the microlens. The Talbot effect permits us to increase the working distance and reduce the period of the patterns. We also demonstrate that the geometries and patterns act as anchor points for cells; affecting the cell adhesion to the metallic substrates and guiding how they spread over the material. View Full-Text
Keywords: laser microstructuring; Talbot effect; biocompatible materials; cell adhesion laser microstructuring; Talbot effect; biocompatible materials; cell adhesion
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Aymerich, M.; Nieto, D.; Álvarez, E.; Flores-Arias, M.T. Laser Surface Microstructuring of Biocompatible Materials Using a Microlens Array and the Talbot Effect: Evaluation of the Cell Adhesion. Materials 2017, 10, 214.

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