Conjugated Polymer Nanoparticles for Bioimaging
AbstractDuring the last decade, conjugated polymers have emerged as an interesting class of fluorescence imaging probes since they generally show high fluorescence brightness, high photostability, fast emission rates, non-blinking behavior and low cytotoxicity. The main concern related to most conjugated polymers is their lack of hydrophilicity and thereby poor bio-availability. This can, however, be overcome by the formulation of conjugated polymer nanoparticles in aqueous medium. This review provides an overview of the different techniques employed for the preparation of conjugated polymer nanoparticles, together with methods to improve their photoluminescence quantum yields. For selective targeting of specific cells, dedicated surface functionalization protocols have been developed, using different functional groups for ligand immobilization. Finally, conjugated polymer nanoparticles have recently also been employed for theranostic applications, wherein the particles are simultaneously used as fluorescent probes and carriers for anti-tumor drugs. View Full-Text
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Braeken, Y.; Cheruku, S.; Ethirajan, A.; Maes, W. Conjugated Polymer Nanoparticles for Bioimaging. Materials 2017, 10, 1420.
Braeken Y, Cheruku S, Ethirajan A, Maes W. Conjugated Polymer Nanoparticles for Bioimaging. Materials. 2017; 10(12):1420.Chicago/Turabian Style
Braeken, Yasmine; Cheruku, Srujan; Ethirajan, Anitha; Maes, Wouter. 2017. "Conjugated Polymer Nanoparticles for Bioimaging." Materials 10, no. 12: 1420.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.