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Mar. Drugs 2010, 8(10), 2639-2646; doi:10.3390/md8102639
Article

Excavatoids O and P, New 12-Hydroxybriaranes from the Octocoral Briareum excavatum

1,2,3,4,5,* , 1,2
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 and
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Received: 7 September 2010 / Revised: 23 September 2010 / Accepted: 9 October 2010 / Published: 12 October 2010
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Abstract

Two new 12-hydroxybriarane diterpenoids, designated as excavatoids O (1) and P (2), were isolated from the octocoral Briareum excavatum. The structures of briaranes 1 and 2 were established on the basis of extensive spectral data analysis. Excavatoid P (2) is the first metabolite which possesses a 6b-chlorine atom in briarane analogues.
Keywords: excavatoid; briarane; octocoral; Briareum excavatum excavatoid; briarane; octocoral; Briareum excavatum
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Sung, P.-J.; Li, G.-Y.; Su, Y.-D.; Lin, M.-R.; Chang, Y.-C.; Kung, T.-H.; Lin, C.-S.; Chen, Y.-H.; Su, J.-H.; Lu, M.-C.; Kuo, J.; Weng, C.-F.; Hwang, T.-L. Excavatoids O and P, New 12-Hydroxybriaranes from the Octocoral Briareum excavatum. Mar. Drugs 2010, 8, 2639-2646.

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