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Mar. Drugs 2009, 7(2), 97-112; doi:10.3390/md7020097

Broad-Spectrum Antimicrobial Epiphytic and Endophytic Fungi from Marine Organisms: Isolation, Bioassay and Taxonomy

Department of Biotechnology, School of Environmental and Chemical Engineering, Dalian Jiaotong University, Dalian 116028, P.R. China
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Received: 26 March 2009 / Revised: 12 April 2009 / Accepted: 16 April 2009 / Published: 17 April 2009
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Abstract

In the search for new marine derived antibiotics, 43 epi- and endophytic fungal strains were isolated from the surface or the inner tissue of different marine plants and invertebrates. Through preliminary and secondary screening, 10 of them were found to be able to produce broad-spectrum antimicrobial metabolites. By morphological and molecular biological methods, three active strains were characterized to be Penicillium glabrum, Fusarium oxysporum, and Alternaria alternata.
Keywords: Epi- and endophytic; marine derived fungi; antimicrobial activity; taxonomy Epi- and endophytic; marine derived fungi; antimicrobial activity; taxonomy
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MDPI and ACS Style

Zhang, Y.; Mu, J.; Feng, Y.; Kang, Y.; Zhang, J.; Gu, P.-J.; Wang, Y.; Ma, L.-F.; Zhu, Y.-H. Broad-Spectrum Antimicrobial Epiphytic and Endophytic Fungi from Marine Organisms: Isolation, Bioassay and Taxonomy. Mar. Drugs 2009, 7, 97-112.

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