Broad-Spectrum Antimicrobial Epiphytic and Endophytic Fungi from Marine Organisms: Isolation, Bioassay and Taxonomy

doi:10.3390/md7020097

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Mar. Drugs 2009, 7(2), 97-112; doi:10.3390/md7020097

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Broad-Spectrum Antimicrobial Epiphytic and Endophytic Fungi from Marine Organisms: Isolation, Bioassay and Taxonomy

Yi Zhang* , Jun Mu, Yan Feng, Yue Kang, Jia Zhang, Peng-Juan Gu, Yu Wang, Li-Fang Ma and Yan-Hua Zhu

Department of Biotechnology, School of Environmental and Chemical Engineering, Dalian Jiaotong University, Dalian 116028, P.R. China

* Author to whom correspondence should be addressed.

Received: 26 March 2009; in revised form: 12 April 2009 / Accepted: 16 April 2009 / Published: 17 April 2009

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Abstract: In the search for new marine derived antibiotics, 43 epi- and endophytic fungal strains were isolated from the surface or the inner tissue of different marine plants and invertebrates. Through preliminary and secondary screening, 10 of them were found to be able to produce broad-spectrum antimicrobial metabolites. By morphological and molecular biological methods, three active strains were characterized to be Penicillium glabrum, Fusarium oxysporum, and Alternaria alternata.

Keywords: Epi- and endophytic; marine derived fungi; antimicrobial activity; taxonomy

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Cite This Article

MDPI and ACS Style

Zhang, Y.; Mu, J.; Feng, Y.; Kang, Y.; Zhang, J.; Gu, P.-J.; Wang, Y.; Ma, L.-F.; Zhu, Y.-H. Broad-Spectrum Antimicrobial Epiphytic and Endophytic Fungi from Marine Organisms: Isolation, Bioassay and Taxonomy. Mar. Drugs 2009, 7, 97-112.

AMA Style

Zhang Y, Mu J, Feng Y, Kang Y, Zhang J, Gu P-J, Wang Y, Ma L-F, Zhu Y-H. Broad-Spectrum Antimicrobial Epiphytic and Endophytic Fungi from Marine Organisms: Isolation, Bioassay and Taxonomy. Marine Drugs. 2009; 7(2):97-112.

Chicago/Turabian Style

Zhang, Yi; Mu, Jun; Feng, Yan; Kang, Yue; Zhang, Jia; Gu, Peng-Juan; Wang, Yu; Ma, Li-Fang; Zhu, Yan-Hua. 2009. "Broad-Spectrum Antimicrobial Epiphytic and Endophytic Fungi from Marine Organisms: Isolation, Bioassay and Taxonomy." Mar. Drugs 7, no. 2: 97-112.

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