Mar. Drugs 2005, 3(1), 1-8; doi:10.3390/md301001
Article

Amphidinolides B4 and B5, Potent Cytotoxic 26-Membered Macrolides from Dinoflagellate Amphidinium Species

Masashi Tsuda 1 , Yuuko Kariya 1 , Rie Iwamoto 1 , Eri Fukushi 2 , Jun Kawabata 2  and Jun’ichi Kobayashi 1,* email
1 Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan 2 Graduate School of Agriculture, Hokkaido University, Sapporo 060-8589, Japan
* Author to whom correspondence should be addressed.
Received: 6 January 2005 / Accepted: 19 February 2005 / Published: 1 March 2005
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Abstract: Two new cytotoxic 26-membered macrolides, amphidinolides B4 (1) and B5 (2), have been isolated from a marine dinoflagellate Amphidinium sp. (strain Y-100), and the structures were elucidated on the basis of detailed analyses of 2D NMR data including 13C−13C correlations.
Keywords: dinoflagellate; Amphidinium sp.; amphidinolides B4 and B5; cytotoxic

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MDPI and ACS Style

Tsuda, M.; Kariya, Y.; Iwamoto, R.; Fukushi, E.; Kawabata, J.; Kobayashi, J. Amphidinolides B4 and B5, Potent Cytotoxic 26-Membered Macrolides from Dinoflagellate Amphidinium Species. Mar. Drugs 2005, 3, 1-8.

AMA Style

Tsuda M, Kariya Y, Iwamoto R, Fukushi E, Kawabata J, Kobayashi J. Amphidinolides B4 and B5, Potent Cytotoxic 26-Membered Macrolides from Dinoflagellate Amphidinium Species. Marine Drugs. 2005; 3(1):1-8.

Chicago/Turabian Style

Tsuda, Masashi; Kariya, Yuuko; Iwamoto, Rie; Fukushi, Eri; Kawabata, Jun; Kobayashi, Jun’ichi. 2005. "Amphidinolides B4 and B5, Potent Cytotoxic 26-Membered Macrolides from Dinoflagellate Amphidinium Species." Mar. Drugs 3, no. 1: 1-8.

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