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Mar. Drugs 2018, 16(6), 205; https://doi.org/10.3390/md16060205

Absolute Configuration Determination of Retroflexanone Using the Advanced Mosher Method and Application of HPLC-NMR

School of Science (Applied Chemistry and Environmental Science), RMIT University, GPO Box 2476, Melbourne, VIC 3001, Australia
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Received: 23 May 2018 / Revised: 6 June 2018 / Accepted: 7 June 2018 / Published: 12 June 2018
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Abstract

The absolute configuration of retroflexanone (1) and a closely related phlorogluinol (2) was established using the advanced Mosher method and by application of HPLC-NMR. HPLC-NMR permitted a small scale Mosher method analysis to be carried out on these unstable phloroglucinols. View Full-Text
Keywords: Mosher; retroflexanone; phloroglucinol; HPLC-NMR; secondary alcohol Mosher; retroflexanone; phloroglucinol; HPLC-NMR; secondary alcohol
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Singleton, C.; Brkljača, R.; Urban, S. Absolute Configuration Determination of Retroflexanone Using the Advanced Mosher Method and Application of HPLC-NMR. Mar. Drugs 2018, 16, 205.

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