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Mar. Drugs 2017, 15(5), 145; doi:10.3390/md15050145

The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea

1
Department of Biology, University of Utah, Salt Lake City 84112, UT, USA
2
Eccles Institute of Human Genetics, University of Utah, Salt Lake City 84112, UT, USA
3
School of Life Sciences and Technology, Institute of Protein Research, Tongji University, Shanghai 200092, China
4
USTAR Center for Genetic Discovery, University of Utah, Salt Lake City 84112, UT, USA
*
Author to whom correspondence should be addressed.
Received: 21 April 2017 / Revised: 15 May 2017 / Accepted: 17 May 2017 / Published: 20 May 2017
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Abstract

The marine cone snail Conus gloriamaris is an iconic species. For over two centuries, its shell was one of the most prized and valuable natural history objects in the world. Today, cone snails have attracted attention for their remarkable venom components. Many conotoxins are proving valuable as research tools, drug leads, and drugs. In this article, we present the venom gland transcriptome of C. gloriamaris, revealing this species’ conotoxin repertoire. More than 100 conotoxin sequences were identified, representing a valuable resource for future drug discovery efforts. View Full-Text
Keywords: venom; conotoxin; Conus; cone snail; Conus gloriamaris venom; conotoxin; Conus; cone snail; Conus gloriamaris
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Robinson, S.D.; Li, Q.; Lu, A.; Bandyopadhyay, P.K.; Yandell, M.; Olivera, B.M.; Safavi-Hemami, H. The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea. Mar. Drugs 2017, 15, 145.

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