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Mar. Drugs 2017, 15(3), 28; doi:10.3390/md15030028

Secondary Metabolites from Polar Organisms

1
College of Life Science, Taishan Medical University, Taian 271016, Shandong, China
2
College of Life Science, Shandong Agricultural University, Taian 271018, Shandong, China
*
Author to whom correspondence should be addressed.
Academic Editor: Orazio Taglialatela-Scafati
Received: 7 January 2017 / Revised: 24 January 2017 / Accepted: 29 January 2017 / Published: 23 February 2017

Abstract

Polar organisms have been found to develop unique defences against the extreme environment environment, leading to the biosynthesis of novel molecules with diverse bioactivities. This review covers the 219 novel natural products described since 2001, from the Arctic and the Antarctic microoganisms, lichen, moss and marine faunas. The structures of the new compounds and details of the source organism, along with any relevant biological activities are presented. Where reported, synthetic and biosynthetic studies on the polar metabolites have also been included. View Full-Text
Keywords: natural products; secondary metabolism; structure elucidation; biological activity; biosynthesis; chemical synthesis natural products; secondary metabolism; structure elucidation; biological activity; biosynthesis; chemical synthesis
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Tian, Y.; Li, Y.-L.; Zhao, F.-C. Secondary Metabolites from Polar Organisms. Mar. Drugs 2017, 15, 28.

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