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Mar. Drugs 2016, 14(3), 58; doi:10.3390/md14030058

Marine Natural Products from New Caledonia—A Review

1
Laboratoire d’Excellence Labex-CORAIL, Institut de Recherche pour le Développement (IRD), UMR ENTROPIE (IRD—Université de La Réunion—CNRS), BP A5, Nouméa Cedex 98848, Nouvelle-Calédonie
2
USR 3151 CNRS, Protein Phosphorylation & Human Diseases, Station Biologique de Roscoff, Sorbonne Universities, UPMC Univ Paris 06, CS 90074, Roscoff Cedex F-29688, France
3
UMR 7272 CNRS, Marine Natural Products Team, Nice Institute of Chemistry (ICN), University Nice Sophia Antipolis, Parc Valrose, Nice Cedex 02 F-06108, France
4
UMR 8227 CNRS, Integrative Biology of Marine Models, Station Biologique de Roscoff, CS 90074, Roscoff Cedex F-29688, France
*
Authors to whom correspondence should be addressed.
Academic Editor: Paul Long
Received: 20 July 2015 / Revised: 23 February 2016 / Accepted: 25 February 2016 / Published: 16 March 2016

Abstract

Marine micro- and macroorganisms are well known to produce metabolites with high biotechnological potential. Nearly 40 years of systematic prospecting all around the New Caledonia archipelago and several successive research programs have uncovered new chemical leads from benthic and planktonic organisms. After species identification, biological and/or pharmaceutical analyses are performed on marine organisms to assess their bioactivities. A total of 3582 genera, 1107 families and 9372 species have been surveyed and more than 350 novel molecular structures have been identified. Along with their bioactivities that hold promise for therapeutic applications, most of these molecules are also potentially useful for cosmetics and food biotechnology. This review highlights the tremendous marine diversity in New Caledonia, and offers an outline of the vast possibilities for natural products, especially in the interest of pursuing collaborative fundamental research programs and developing local biotechnology programs. View Full-Text
Keywords: New Caledonia; marine biodiversity; bioactive molecules pipeline; chemodiversity; coral reefs New Caledonia; marine biodiversity; bioactive molecules pipeline; chemodiversity; coral reefs
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Motuhi, S.-E.; Mehiri, M.; Payri, C.E.; La Barre, S.; Bach, S. Marine Natural Products from New Caledonia—A Review. Mar. Drugs 2016, 14, 58.

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