Next Article in Journal
Structure and Effects of Cyanobacterial Lipopolysaccharides
Previous Article in Journal
Functional and Structural Characterization of FAU Gene/Protein from Marine Sponge Suberites domuncula
Article Menu

Export Article

Open AccessArticle
Mar. Drugs 2015, 13(7), 4197-4216; doi:10.3390/md13074197

Red Algae (Rhodophyta) from the Coast of Madagascar: Preliminary Bioactivity Studies and Isolation of Natural Products

1
Department Chemie, Technische Universität Dresden, Bergstr. 66, 01069 Dresden, Germany
2
Centre National de Recherche sur l'Environnement, MESupRes, BP 1739, Antananarivo 101, Madagascar
3
Laboratoire de Chimie Appliquée aux Substances Naturelles, Faculté des Sciences, Université d'Antananarivo, BP 566, Antananarivo 101, Madagascar
*
Author to whom correspondence should be addressed.
Academic Editor: Anake Kijjoa
Received: 25 March 2015 / Revised: 18 June 2015 / Accepted: 25 June 2015 / Published: 7 July 2015
View Full-Text   |   Download PDF [364 KB, uploaded 8 July 2015]   |  

Abstract

Several species of red algae (Rhodophyta) from the coastal regions of Madagascar have been investigated for their natural products. The most abundant compound was cholesterol (5) in combination with a series of oxidized congeners. The brominated indoles 13 along with the sesquiterpene debilone (4) have been isolated from Laurencia complanata. For the first time, debilone (4) has been obtained from a marine plant. From the methanol extract of Calloseris sp., we have achieved the second isolation of the unusual A-ring contracted steroids (−)-2-ethoxycarbonyl-2β-hydroxy-A-nor-cholest-5-en-4-one (9) and phorbasterone B (10). The crude extracts of Laurencia complanata exhibited antimicrobial activity against Bacillus cereus, Staphylococcus aureus, Streptococcus pneumoniae, and Candida albicans. View Full-Text
Keywords: algae; indole alkaloids; steroids; NMR spectroscopy; antimicrobial activity algae; indole alkaloids; steroids; NMR spectroscopy; antimicrobial activity
Figures

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary material

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Rahelivao, M.P.; Gruner, M.; Andriamanantoanina, H.; Andriamihaja, B.; Bauer, I.; Knölker, H.-J. Red Algae (Rhodophyta) from the Coast of Madagascar: Preliminary Bioactivity Studies and Isolation of Natural Products. Mar. Drugs 2015, 13, 4197-4216.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Mar. Drugs EISSN 1660-3397 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top