Next Article in Journal
Paper Synthesis, Cytotoxicity and Apoptosis Induction in Human Tumor Cells by Galaxamide and Its Analogues
Next Article in Special Issue
Synthetic Biology and Metabolic Engineering for Marine Carotenoids: New Opportunities and Future Prospects
Previous Article in Journal
Oxygenated Eremophilane- and Neolemnane-Derived Sesquiterpenoids from the Soft Coral Lemnalia philippinensis
Previous Article in Special Issue
Fucoxanthin Enhances the Level of Reduced Glutathione via the Nrf2-Mediated Pathway in Human Keratinocytes
Article Menu

Export Article

Open AccessArticle
Mar. Drugs 2014, 12(8), 4504-4520; doi:10.3390/md12084504

Accumulation of Astaxanthin by a New Haematococcus pluvialis Strain BM1 from the White Sea Coastal Rocks (Russia)

1
Biological Faculty of Lomonosov Moscow State University, 1/12 Leninskie Gori, Moscow 119234, Russia
2
Timiryazev Institute of Plant Physiology, Russian Academy of Sciences, 35, Botanicheskaya str., Moscow 127276, Russia
*
Author to whom correspondence should be addressed.
Received: 12 June 2014 / Revised: 17 July 2014 / Accepted: 4 August 2014 / Published: 15 August 2014
(This article belongs to the Special Issue Marine Carotenoids (Special Issue))
View Full-Text   |   Download PDF [1820 KB, uploaded 24 February 2015]   |  

Abstract

We report on a novel arctic strain BM1 of a carotenogenic chlorophyte from a coastal habitat with harsh environmental conditions (wide variations in solar irradiance, temperature, salinity and nutrient availability) identified as Haematococcus pluvialis Flotow. Increased (25‰) salinity exerted no adverse effect on the growth of the green BM1 cells. Under stressful conditions (high light, nitrogen and phosphorus deprivation), green vegetative cells of H. pluvialis BM1 grown in BG11 medium formed non-motile palmelloid cells and, eventually, hematocysts capable of a massive accumulation of the keto-carotenoid astaxanthin with a high nutraceutical and therapeutic potential. Routinely, astaxanthin was accumulated at the level of 4% of the cell dry weight (DW), reaching, under prolonged stress, 5.5% DW. Astaxanthin was predominantly accumulated in the form of mono- and diesters of fatty acids from C16 and C18 families. The palmelloids and hematocysts were characterized by the formation of red-colored cytoplasmic lipid droplets, increasingly large in size and number. The lipid droplets tended to merge and occupied almost the entire volume of the cell at the advanced stages of stress-induced carotenogenesis. The potential application of the new strain for the production of astaxanthin is discussed in comparison with the H. pluvialis strains currently employed in microalgal biotechnology. View Full-Text
Keywords: astaxanthin; carotenogenesis; fatty acids; green microalgae astaxanthin; carotenogenesis; fatty acids; green microalgae
Figures

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Supplementary material

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Chekanov, K.; Lobakova, E.; Selyakh, I.; Semenova, L.; Sidorov, R.; Solovchenko, A. Accumulation of Astaxanthin by a New Haematococcus pluvialis Strain BM1 from the White Sea Coastal Rocks (Russia). Mar. Drugs 2014, 12, 4504-4520.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Mar. Drugs EISSN 1660-3397 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top