Next Article in Journal
Chlorella zofingiensis as an Alternative Microalgal Producer of Astaxanthin: Biology and Industrial Potential
Previous Article in Journal
Chromomycins A2 and A3 from Marine Actinomycetes with TRAIL Resistance-Overcoming and Wnt Signal Inhibitory Activities
Article Menu

Export Article

Open AccessCommunication
Mar. Drugs 2014, 12(6), 3477-3486; doi:10.3390/md12063477

Cespitulones A and B, Cytotoxic Diterpenoids of a New Structure Class from the Soft Coral Cespitularia taeniata

School of Pharmacy, College of Medicine, National Taiwan University, Taipei 100, Taiwan
Department of Life Sciences, National Cheng Kung University, No. 1 University Road, Tainan 701, Taiwan
Department of Marine Biotechnology and Resources, National Sun Yat-Sen University, Kaohsiung 804, Taiwan
Division of Herbal Drugs and Natural Products, National Research Institute of Chinese Medicine, Taipei 112, Taiwan
Author to whom correspondence should be addressed.
Received: 2 April 2014 / Revised: 9 May 2014 / Accepted: 12 May 2014 / Published: 5 June 2014
View Full-Text   |   Download PDF [807 KB, uploaded 24 February 2015]   |  


Two novel diterpenoids, cespitulones A (1) and B (2), were isolated from extracts of the soft coral Cespitularia taeniata. Both compounds possess an unprecedented bicyclo [10.3.1] ring system with C-C bond connections between C-10 and C-20, and between C-20 and C-11. Their structures were elucidated on the basis of extensive spectroscopic analyses. Compound 1 exhibited significant cytotoxicity against human medulloblastoma and colon adenocarcinoma cancer cells. View Full-Text
Keywords: Cespitularia taeniata; diterpenoid; cespitulone; cytotoxicity Cespitularia taeniata; diterpenoid; cespitulone; cytotoxicity

Figure 1

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Lin, Y.-C.; Wang, S.-S.; Chen, C.-H.; Kuo, Y.-H.; Shen, Y.-C. Cespitulones A and B, Cytotoxic Diterpenoids of a New Structure Class from the Soft Coral Cespitularia taeniata. Mar. Drugs 2014, 12, 3477-3486.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Mar. Drugs EISSN 1660-3397 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top