Mar. Drugs 2014, 12(2), 589-600; doi:10.3390/md12020589
Article

Briarane Diterpenes from the South China Sea Gorgonian Coral, Junceella gemmacea

Received: 12 December 2013; in revised form: 13 January 2014 / Accepted: 15 January 2014 / Published: 27 January 2014
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Four new briarane diterpenoids, junceellolides M–P (14), were isolated together with seven known analogs (511) from the South China Sea gorgonian, Junceella gemmacea. The structures of these compounds were elucidated by detailed spectroscopic analysis and comparison with the reported data. The absolute configuration of compounds 13 were determined based on an ECD experiment, while the absolute configuration of compound 4 was genetically determined. All the compounds were isolated for the first time from J. gemmacea. These compounds showed no growth inhibitory activity against A549, MG63 and SMMC-7721 cell lines in an in vitro bioassay.
Keywords: Junceella gemmacea; briarane; diterpenoid; junceellolide
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MDPI and ACS Style

Zhou, W.; Li, J.; E, H.-C.; Liu, B.-S.; Tang, H.; Gerwick, W.H.; Hua, H.-M.; Zhang, W. Briarane Diterpenes from the South China Sea Gorgonian Coral, Junceella gemmacea. Mar. Drugs 2014, 12, 589-600.

AMA Style

Zhou W, Li J, E H-C, Liu B-S, Tang H, Gerwick WH, Hua H-M, Zhang W. Briarane Diterpenes from the South China Sea Gorgonian Coral, Junceella gemmacea. Marine Drugs. 2014; 12(2):589-600.

Chicago/Turabian Style

Zhou, Wei; Li, Jiao; E, Heng-Chao; Liu, Bao-Shu; Tang, Hua; Gerwick, William H.; Hua, Hui-Ming; Zhang, Wen. 2014. "Briarane Diterpenes from the South China Sea Gorgonian Coral, Junceella gemmacea." Mar. Drugs 12, no. 2: 589-600.

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