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Diversity 2010, 2(4), 679-700; doi:10.3390/d2040679
Review

Insights into Hemoglobin Polymorphism and Related Functional Effects on Hematological Pattern in Mediterranean Cattle, Goat and Sheep

1,* , 1
 and 2
Received: 3 March 2010; in revised form: 16 April 2010 / Accepted: 19 April 2010 / Published: 22 April 2010
(This article belongs to the Special Issue Biological Diversity Assessed by Molecular Methods)
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Abstract: This report is a review of some of the results obtained over the course of 20 years spent investigating hemoglobin phenotypes and the related functional effects on hematological patterns in ruminant breeds. Tests included qualitative and quantitative analyses of hemoglobins and qualitative and quantitative analyses of α and β globins, as well as hemochromocytometric analysis. Understanding the adaptive significance of the hemoglobin variants was the goal of most of these investigations. The advances presented in this review and the previously unpublished findings included here provide evidence that Mediterranean breeds exhibit a fair number of positively charged variants, whose possible adaptive significance is discussed.
Keywords: cattle; goat; sheep; alpha globin genes; beta globin genes; positively charged variants hematocrit value cattle; goat; sheep; alpha globin genes; beta globin genes; positively charged variants hematocrit value
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Pieragostini, E.; Alloggio, I.; Petazzi, F. Insights into Hemoglobin Polymorphism and Related Functional Effects on Hematological Pattern in Mediterranean Cattle, Goat and Sheep. Diversity 2010, 2, 679-700.

AMA Style

Pieragostini E, Alloggio I, Petazzi F. Insights into Hemoglobin Polymorphism and Related Functional Effects on Hematological Pattern in Mediterranean Cattle, Goat and Sheep. Diversity. 2010; 2(4):679-700.

Chicago/Turabian Style

Pieragostini, Elisa; Alloggio, Ingrid; Petazzi, Ferruccio. 2010. "Insights into Hemoglobin Polymorphism and Related Functional Effects on Hematological Pattern in Mediterranean Cattle, Goat and Sheep." Diversity 2, no. 4: 679-700.


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