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Molbank 2013, 2013(4), M811; doi:10.3390/M811
Short Note

Ethyl 2-(3-Methyl-5-oxo-4,5-dihydro-3H-benzo[e][1,4]diazepin-2-ylamino)benzoate

1,2,*  and 1
Received: 25 October 2013; Accepted: 9 December 2013 / Published: 12 December 2013
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Abstract: A simple route for synthesis of ethyl 2-(3-methyl-5-oxo-4,5-dihydro-3H-benzo[e][1,4]diazepin-2-ylamino)benzoate is developed. The present work involves condensation of 2-(2-nitrobenzamido)propanoic acid with ethyl anthranillate followed by the H2/Pd/C reduction to give the amino ester which upon heating in DMF in the presence of FeCl3 affords the title compound. The structure of the title compound was established on the basis of 1H-NMR, 13C-NMR and mass spectral data.
Keywords: benzo[e][1,4]diazepine; ferric chloride; cyclization benzo[e][1,4]diazepine; ferric chloride; cyclization
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MDPI and ACS Style

Al-Said, N.H.; Al-Sghair, A.M. Ethyl 2-(3-Methyl-5-oxo-4,5-dihydro-3H-benzo[e][1,4]diazepin-2-ylamino)benzoate. Molbank 2013, 2013, M811.

AMA Style

Al-Said NH, Al-Sghair AM. Ethyl 2-(3-Methyl-5-oxo-4,5-dihydro-3H-benzo[e][1,4]diazepin-2-ylamino)benzoate. Molbank. 2013; 2013(4):M811.

Chicago/Turabian Style

Al-Said, Naim H.; Al-Sghair, Ayat M. 2013. "Ethyl 2-(3-Methyl-5-oxo-4,5-dihydro-3H-benzo[e][1,4]diazepin-2-ylamino)benzoate." Molbank 2013, no. 4: M811.


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