Molbank 2013, 2013(3), M805; doi:10.3390/M805
Short Note

3-Chloro-4-(5-methoxy-1H-indol-3-yl)cyclobut-3-ene-1,2-dione

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Received: 18 April 2013; Accepted: 10 July 2013 / Published: 22 July 2013
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: The indole ring system is a prominent partial structure of several protein kinase inhibitor families. The title compound is the first example of a 5-substituted indolyl squaryl chloride with free indole nitrogen. It has been synthesized by reaction of 5-methoxyindole with squaric acid dichloride in diethyl ether and its IR, 1H-NMR, 13C-NMR, MS, UV and HPLC data are presented. This compound may prove to be a rather useful building block for the preparation of various derivatives for biological studies.
Keywords: Friedel-Crafts acylation; indole; squaric acid dichloride
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MDPI and ACS Style

Lande, D.H.; Messal, M.; Reimann, V.; Renger, C.; Rurka, C.; Schoemaker, J.; Schröder, N.K.; Grünefeld, J. 3-Chloro-4-(5-methoxy-1H-indol-3-yl)cyclobut-3-ene-1,2-dione. Molbank 2013, 2013, M805.

AMA Style

Lande DH, Messal M, Reimann V, Renger C, Rurka C, Schoemaker J, Schröder NK, Grünefeld J. 3-Chloro-4-(5-methoxy-1H-indol-3-yl)cyclobut-3-ene-1,2-dione. Molbank. 2013; 2013(3):M805.

Chicago/Turabian Style

Lande, Duc H.; Messal, Marleen; Reimann, Vincent; Renger, Caren; Rurka, Constanze; Schoemaker, Jana; Schröder, Nadin K.; Grünefeld, Johann. 2013. "3-Chloro-4-(5-methoxy-1H-indol-3-yl)cyclobut-3-ene-1,2-dione." Molbank 2013, no. 3: M805.

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