Next Article in Journal
6,6'-(1E,1'E)-((1R,2R)-1,2-Diphenylethane-1,2-diyl)bis(azan-1-yl-1-ylidene)bis(methan-1-yl-1-ylidene)bis(2-tert-butyl-4-((trimethylsilyl)ethynyl)phenol)
Previous Article in Journal
Benzyl 3-deoxy-3-(3,4,5-trimethoxybenzylamino)-β-L-xylopyranoside
Molbank 2013, 2013(1), M794; doi:10.3390/M794
Short Note

2-(4-Methylpiperazin-1-yl)-4-phenyl-6-(thiophen-2-yl)-pyridine-3-carbonitrile

1,*  and 2
Received: 19 December 2012 / Accepted: 18 February 2013 / Published: 27 February 2013
Download PDF [374 KB, uploaded 27 February 2013]

Abstract

2-(4-Methylpiperazin-1-yl)-4-phenyl-6-(thiophen-2-yl)-pyridine-3-carbonitrile (4) was synthesized via nucleophilic substitution reaction of 1-methylpiperazine with 2-bromo analogue 3. The latter was obtained through bromination (Br2/AcOH) of 2-[3-oxo-1-phenyl-3-(thiophen-2-yl)propyl]malononitrile (2).
Keywords: 2-propen-1-one; pyridine-3-carbonitrile; single crystal X-ray 2-propen-1-one; pyridine-3-carbonitrile; single crystal X-ray
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplements

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote
MDPI and ACS Style

Mishriky, N.; Moustafa, A.M. 2-(4-Methylpiperazin-1-yl)-4-phenyl-6-(thiophen-2-yl)-pyridine-3-carbonitrile. Molbank 2013, 2013, M794.

View more citation formats

Article Metrics

For more information on the journal, click here

Comments

Cited By

[Return to top]
Molbank EISSN 1422-8599 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert