2-(4-Methylpiperazin-1-yl)-4-phenyl-6-(thiophen-2-yl)-pyridine-3-carbonitrile

doi:10.3390/M794

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Molbank 2013, 2013(1), M794; doi:10.3390/M794

Short Note

2-(4-Methylpiperazin-1-yl)-4-phenyl-6-(thiophen-2-yl)-pyridine-3-carbonitrile

Nawal Mishriky^1,* and Aisha M. Moustafa²

¹ Chemistry of Pesticides Department, National Research Centre, Dokki, Cairo 12622, Egypt ² Solid State Physics Department, National Research Centre, Dokki, Cairo 12622, Egypt

* Author to whom correspondence should be addressed.

Received: 19 December 2012 / Accepted: 18 February 2013 / Published: 27 February 2013

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Abstract: 2-(4-Methylpiperazin-1-yl)-4-phenyl-6-(thiophen-2-yl)-pyridine-3-carbonitrile (4) was synthesized via nucleophilic substitution reaction of 1-methylpiperazine with 2-bromo analogue 3. The latter was obtained through bromination (Br₂/AcOH) of 2-[3-oxo-1-phenyl-3-(thiophen-2-yl)propyl]malononitrile (2).

Keywords: 2-propen-1-one; pyridine-3-carbonitrile; single crystal X-ray

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MDPI and ACS Style

Mishriky, N.; Moustafa, A.M. 2-(4-Methylpiperazin-1-yl)-4-phenyl-6-(thiophen-2-yl)-pyridine-3-carbonitrile. Molbank 2013, 2013, M794.

AMA Style

Mishriky N, Moustafa AM. 2-(4-Methylpiperazin-1-yl)-4-phenyl-6-(thiophen-2-yl)-pyridine-3-carbonitrile. Molbank. 2013; 2013(1):M794.

Chicago/Turabian Style

Mishriky, Nawal; Moustafa, Aisha M. 2013. "2-(4-Methylpiperazin-1-yl)-4-phenyl-6-(thiophen-2-yl)-pyridine-3-carbonitrile." Molbank 2013, no. 1: M794.

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