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Molbank 2012, 2012(3), M769; doi:10.3390/M769
Short Note

N-(3,4-Dimethoxyphenyl)-4-oxo-2,3,7-triazaspiro[4.5]dec-1-ene-1-carboxamide Hydrochloride

1,2, 1,* , 1 and 3
1 Department of Studies in Chemistry, Mangalore University, Mangalagangotri-574 199, Karnataka, India 2 Aurigene Discovery Technologies Limited, Electronics city, Phase-II, Bangalore-560 100, Karnataka, India 3 Research Department of Chemistry, P. A College of Engineering, Nadupadavu, Mangalore 574153, Karnataka, India
* Author to whom correspondence should be addressed.
Received: 29 May 2012 / Accepted: 3 August 2012 / Published: 8 August 2012
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A simple and novel route for synthesis of new spirocyclic amide derivative is developed. The present work involves the oxidative cleavage of tert-butyl 1-(furan-2-yl)-4-oxo-2,3,7-triazaspiro[4.5]dec-1-ene-7-carboxylate 1 followed by the amine coupling and deprotection of Boc.
Keywords: spirocyclic; pyrazolone; oxidation; amide spirocyclic; pyrazolone; oxidation; amide
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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Srinivasan, R.; Narayana, B.; Samshuddin, S.; Sarojini, B.K. N-(3,4-Dimethoxyphenyl)-4-oxo-2,3,7-triazaspiro[4.5]dec-1-ene-1-carboxamide Hydrochloride. Molbank 2012, 2012, M769.

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