7-(3-Chlorophenylamino)-1-cyclopropyl-6-fluoro-8-nitro-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid

doi:10.3390/M669

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Molbank 2010, 2010(2), M669; doi:10.3390/M669

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7-(3-Chlorophenylamino)-1-cyclopropyl-6-fluoro-8-nitro-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid

Yusuf Mohammad Al-Hiari^1,* , Amjad M. Qandil², Rufaida M. Al-Zoubi¹, Muhammed H. Alzweiri¹, Rula M. Darwish¹, Ghassan F. Shattat³ and Tariq M. Al-Qirim³

¹ Faculty of Pharmacy, University of Jordan, Amman-11942, Jordan ² Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan ³ Faculty of Pharmacy, Al-Zaytoonah Private University of Jordan, Amman-11733, Jordan

* Author to whom correspondence should be addressed.

Received: 8 March 2010 / Accepted: 22 March 2010 / Published: 24 March 2010

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Abstract: 7-(3-Chlorophenylamino)-1-cyclopropyl-6-fluoro-8-nitro-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid (2) was prepared and fully characterized by NMR, IR, and MS. Compound 2 exhibited good antibacterial activity against gram-positive standard and resistant strains.

Keywords: 7-anilinofluoroquinolone; fluoroquinolone; antibacterial

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Cite This Article

MDPI and ACS Style

Al-Hiari, Y.M.; Qandil, A.M.; Al-Zoubi, R.M.; Alzweiri, M.H.; Darwish, R.M.; Shattat, G.F.; Al-Qirim, T.M. 7-(3-Chlorophenylamino)-1-cyclopropyl-6-fluoro-8-nitro-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid. Molbank 2010, 2010, M669.

AMA Style

Al-Hiari YM, Qandil AM, Al-Zoubi RM, Alzweiri MH, Darwish RM, Shattat GF, Al-Qirim TM. 7-(3-Chlorophenylamino)-1-cyclopropyl-6-fluoro-8-nitro-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid. Molbank. 2010; 2010(2):M669.

Chicago/Turabian Style

Al-Hiari, Yusuf Mohammad; Qandil, Amjad M.; Al-Zoubi, Rufaida M.; Alzweiri, Muhammed H.; Darwish, Rula M.; Shattat, Ghassan F.; Al-Qirim, Tariq M. 2010. "7-(3-Chlorophenylamino)-1-cyclopropyl-6-fluoro-8-nitro-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid." Molbank 2010, no. 2: M669.

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