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4,6-Diamino-5-(4-methylbenzylidene)pyrimidin-2(5H)-one
Molbank 2010, 2010(1), M654; doi:10.3390/M654
Short Note

1-[4-[Bis(2-chloroethyl)amino]benzyl]-5,5-dimethyl-2,5-dihydro-4H-benzo[e]isoindol-4-one (Cytotoxic Oxonaphthalene-pyrroles, Part II)

*  and
Department of Drug and Natural Product Synthesis, Faculty of Life Sciences, University of Vienna, Althanstra├če 14, A- 1090 Vienna, Austria
* Author to whom correspondence should be addressed.
Received: 4 December 2009 / Accepted: 26 January 2010 / Published: 29 January 2010
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Abstract

A bis(chloroethyl)amine-containing side chain is attached to an oxonaphthalene-annelated pyrrole in expectation of DNA alkylating properties. The cytotoxicity is evaluated against two cell lines, KB-31 and KB-8511, respectively.
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Spreitzer, H.; Puschmann, C. 1-[4-[Bis(2-chloroethyl)amino]benzyl]-5,5-dimethyl-2,5-dihydro-4H-benzo[e]isoindol-4-one (Cytotoxic Oxonaphthalene-pyrroles, Part II). Molbank 2010, 2010, M654.

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