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Molbank 2008, 2008(3), M579; doi:10.3390/M579
Short Note

Determination of the Absolute Configurations of (+)-N-((3S)-3- {[(4-methylphenyl)sulfonyl]amino}-1-oxaspiro[4.5]deca-6,9- dien-2,8-dion-7-yl) Acetamide and Benzamide

1,* , 1 and 2
Received: 18 September 2008 / Accepted: 3 November 2008 / Published: 7 November 2008
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Abstract

We recently reported the asymmetric synthesis of the two title compounds without the configurational assignments of the newly formed chiral spirocarbons. We now wish to report that both compounds have a (R)-configuration at the spirocarbon based on 1D and 2D nuclear Overhauser enhancement (nOe) experiments.
Keywords: Spiroannulation; stereochemistry; nOe; NMR; absolute configuration Spiroannulation; stereochemistry; nOe; NMR; absolute configuration
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Plourde, G.L.; Susag, L.M.; Dick, D.G. Determination of the Absolute Configurations of (+)-N-((3S)-3- {[(4-methylphenyl)sulfonyl]amino}-1-oxaspiro[4.5]deca-6,9- dien-2,8-dion-7-yl) Acetamide and Benzamide. Molbank 2008, 2008, M579.

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