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Molbank 2008, 2008(3), M579; doi:10.3390/M579
Short Note

Determination of the Absolute Configurations of (+)-N-((3S)-3- {[(4-methylphenyl)sulfonyl]amino}-1-oxaspiro[4.5]deca-6,9- dien-2,8-dion-7-yl) Acetamide and Benzamide

1,* , 1 and 2
1 University of Northern British Columbia, Department of Chemistry, 3333 University Way, Prince George, British Columbia, V2N 4Z9, Canada 2 College of the Rockies, University Studies (Chemistry), Box 8500, Cranbrook, British Columbia, V1C 5L7, Canada
* Author to whom correspondence should be addressed.
Received: 18 September 2008 / Accepted: 3 November 2008 / Published: 7 November 2008
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Abstract

We recently reported the asymmetric synthesis of the two title compounds without the configurational assignments of the newly formed chiral spirocarbons. We now wish to report that both compounds have a (R)-configuration at the spirocarbon based on 1D and 2D nuclear Overhauser enhancement (nOe) experiments.
Keywords: Spiroannulation; stereochemistry; nOe; NMR; absolute configuration Spiroannulation; stereochemistry; nOe; NMR; absolute configuration
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Plourde, G.L.; Susag, L.M.; Dick, D.G. Determination of the Absolute Configurations of (+)-N-((3S)-3- {[(4-methylphenyl)sulfonyl]amino}-1-oxaspiro[4.5]deca-6,9- dien-2,8-dion-7-yl) Acetamide and Benzamide. Molbank 2008, 2008, M579.

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