Synthesis of 4,4'-(Cyclohexane-1,1-diyl)bis(1-methyl- 1H-pyrazol-5-ol)

doi:10.3390/M569

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Molbank 2008, 2008(2), M569; doi:10.3390/M569

Short Note

Synthesis of 4,4'-(Cyclohexane-1,1-diyl)bis(1-methyl- 1H-pyrazol-5-ol)

Gernot A. Eller* and Wolfgang Holzer

Department of Drug and Natural Product Synthesis, University of Vienna, Althanstrasse 14, A-1090 Vienna, Austria

* Author to whom correspondence should be addressed.

Received: 1 July 2008 / Accepted: 19 August 2008 / Published: 22 August 2008

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Abstract: Methyl (2E)-3-methoxyacrylate and excess methylhydrazine yield crude 1- methyl-2-pyrazolin-5-one which is reacted with cyclohexanone to obtain the title compound in 86% yield. Detailed spectroscopic data (1H NMR, 13C NMR, 15N NMR, and MS) are presented.

Keywords: Pyrazolones; cyclohexanone adduct; NMR spectroscopy

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Supplementary File 1:
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3D structure generated by CORINA by Molecular Networks.
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Supplementary File 3:
569-2.mol 3D structure (MOL, 2 KB) Display in MOL Viewer
3D structure generated by CORINA by Molecular Networks.
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Cite This Article

MDPI and ACS Style

Eller, G.A.; Holzer, W. Synthesis of 4,4'-(Cyclohexane-1,1-diyl)bis(1-methyl- 1H-pyrazol-5-ol). Molbank 2008, 2008, M569.

AMA Style

Eller GA, Holzer W. Synthesis of 4,4'-(Cyclohexane-1,1-diyl)bis(1-methyl- 1H-pyrazol-5-ol). Molbank. 2008; 2008(2):M569.

Chicago/Turabian Style

Eller, Gernot A.; Holzer, Wolfgang. 2008. "Synthesis of 4,4'-(Cyclohexane-1,1-diyl)bis(1-methyl- 1H-pyrazol-5-ol)." Molbank 2008, no. 2: M569.

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