Synthesis and Physical Characterization of (E)-1-(3-morpholinopropyl)-3-phenoxy-4-styrylazetidine-2-one as the First β-lactam Bearing a Morpholino Moiety

doi:10.3390/M542

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Molbank 2007, 2007(2), M542; doi:10.3390/M542

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Synthesis and Physical Characterization of (E)-1-(3-morpholinopropyl)-3-phenoxy-4-styrylazetidine-2-one as the First β-lactam Bearing a Morpholino Moiety

Aliasghar Jarrahpour^1,* , Abraham F. Jalbout² and Masomeh Eskandari¹

¹ epartment of Chemistry, College of Sciences, Shiraz University, Shiraz 71454, Iran ² Department of Chemistry, University of Arizona, Tucson, AZ 85721 USA

* Author to whom correspondence should be addressed.

Received: 3 January 2007 / Accepted: 27 February 2007 / Published: 31 May 2007

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Abstract: In this paper we propose the synthesis of (E)-1-(3-morpholinopropyl)-3-phenoxy-4-styryl azetidine-2-one as a new monocyclic β-lactam. Its structure has been confirmed by IR, 1H-NMR, 13C-NMR and Mass spectroscopic data. In addition to its synthesis we present AM1 calculation to characterize the physical properties of the molecule.

Keywords: Azetidine-2-one; N-morpholinopropyl monocyclic β-lactam; Staudinger reaction; AM1

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3D structure generated by CORINA by Molecular Networks.
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Cite This Article

MDPI and ACS Style

Jarrahpour, A.; Jalbout, A.F.; Eskandari, M. Synthesis and Physical Characterization of (E)-1-(3-morpholinopropyl)-3-phenoxy-4-styrylazetidine-2-one as the First β-lactam Bearing a Morpholino Moiety. Molbank 2007, 2007, M542.

AMA Style

Jarrahpour A, Jalbout AF, Eskandari M. Synthesis and Physical Characterization of (E)-1-(3-morpholinopropyl)-3-phenoxy-4-styrylazetidine-2-one as the First β-lactam Bearing a Morpholino Moiety. Molbank. 2007; 2007(2):M542.

Chicago/Turabian Style

Jarrahpour, Aliasghar; Jalbout, Abraham F.; Eskandari, Masomeh. 2007. "Synthesis and Physical Characterization of (E)-1-(3-morpholinopropyl)-3-phenoxy-4-styrylazetidine-2-one as the First β-lactam Bearing a Morpholino Moiety." Molbank 2007, no. 2: M542.

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