Next Article in Journal
2-(Pyrazin-2-yliminomethyl)phenol
Previous Article in Journal
Synthesis of New Schiff Base: 4-[(Pyridin-3-ylmethylene)- amino]phenyldodecanoate
Molbank 2007, 2007(1), M522; doi:10.3390/M522
Short Note

Electrophilic Substitution at C(7) of a Protected 7-Deaza-2’-deoxyguanosine – The 2’-Deoxyribonucleoside Parent Analogue of Queuosine #

 and *
Organische Chemie I – Bioorganische Chemie, Institut für Chemie, Fachbereich Biologie/Chemie, Universität Osnabrück, Barbarastr. 7, D-49069 Osnabrück, Germany
* Author to whom correspondence should be addressed.
Received: 28 March 2007 / Accepted: 4 April 2007 / Published: 23 April 2007
Download PDF [129 KB, uploaded 19 February 2009]
SciFeed

Abstract

In this manuscript we report on the regioselective electrophilic substitution at C(7) of 7-[2-deoxy-3,5-bis-O-(2-methylpropanoyl)-ß-D-erythro-pentofuranosyl]-2-(formylamino)-4-methoxy-7H-pyrrolo[2,3-d]pyrimidine (2) – a protected precursor of 7-deaza-2’-deoxyguanosine - using N,N-dimethyl-methyleniminium iodide (Eschenmoser’s salt) yielding the Mannich compound 4.
Keywords: 7-Deazapurine; Mannich bases; Eschenmoser’s Salt 7-Deazapurine; Mannich bases; Eschenmoser’s Salt
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Supplementary materials

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote |
RIS
MDPI and ACS Style

Ramzaeva, N.; Rosemeyer, H. Electrophilic Substitution at C(7) of a Protected 7-Deaza-2’-deoxyguanosine – The 2’-Deoxyribonucleoside Parent Analogue of Queuosine #. Molbank 2007, 2007, M522.

View more citation formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Metrics

For more information on the journal, click here

Comments

[Return to top]
Molbank EISSN 1422-8599 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert