Molbank 2007, 2007(1), M522; doi:10.3390/M522
Short Note

Electrophilic Substitution at C(7) of a Protected 7-Deaza-2’-deoxyguanosine – The 2’-Deoxyribonucleoside Parent Analogue of Queuosine #

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Received: 28 March 2007; Accepted: 4 April 2007 / Published: 23 April 2007
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: In this manuscript we report on the regioselective electrophilic substitution at C(7) of 7-[2-deoxy-3,5-bis-O-(2-methylpropanoyl)-ß-D-erythro-pentofuranosyl]-2-(formylamino)-4-methoxy-7H-pyrrolo[2,3-d]pyrimidine (2) – a protected precursor of 7-deaza-2’-deoxyguanosine - using N,N-dimethyl-methyleniminium iodide (Eschenmoser’s salt) yielding the Mannich compound 4.
Keywords: 7-Deazapurine; Mannich bases; Eschenmoser’s Salt
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MDPI and ACS Style

Ramzaeva, N.; Rosemeyer, H. Electrophilic Substitution at C(7) of a Protected 7-Deaza-2’-deoxyguanosine – The 2’-Deoxyribonucleoside Parent Analogue of Queuosine #. Molbank 2007, 2007, M522.

AMA Style

Ramzaeva N, Rosemeyer H. Electrophilic Substitution at C(7) of a Protected 7-Deaza-2’-deoxyguanosine – The 2’-Deoxyribonucleoside Parent Analogue of Queuosine #. Molbank. 2007; 2007(1):M522.

Chicago/Turabian Style

Ramzaeva, Natalya; Rosemeyer, Helmut. 2007. "Electrophilic Substitution at C(7) of a Protected 7-Deaza-2’-deoxyguanosine – The 2’-Deoxyribonucleoside Parent Analogue of Queuosine #." Molbank 2007, no. 1: M522.

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