QSAR of Some N1-Aryl/Heteroarylaminomethyl/ethyl-1,2,4-Triazoles Part II: Antimicrobial Activity Against BacillusSubtilis

doi:10.3390/i7040119

This article is

freely available
re-usable

Int. J. Mol. Sci. 2006, 7(4), 119-129; doi:10.3390/i7040119

Article

QSAR of Some N¹-Aryl/Heteroarylaminomethyl/ethyl-1,2,4-Triazoles Part II: Antimicrobial Activity Against BacillusSubtilis

Vesna Dimova ¹^,* , Katica C. Ragenovic ¹ and Vladimir Kakurinov ²

¹ Faculty of Technology and Metallurgy, The “Sv. Kiril & Metodij” University, Ruger Boskovic 16, 1000 Skopje, Macedonia ² Faculty of Agriculture, Department of Microbiology, The “Sv. Kiril & Metodij” University, bul. Aleksandar Makedonski, bb, 1000 Skopje, Macedonia

* Author to whom correspondence should be addressed.

Received: 27 December 2005; in revised form: 15 August 2006 / Accepted: 20 April 2006 / Published: 26 April 2006

Download PDF Full-Text [80 KB, uploaded 20 June 2008 16:51 CET]

Abstract: QSAR analysis of a series of previously synthesized N¹-aryl-amino/methyl/ethyl-1,2,4-triazole and N¹-heteroarylamino/methyl/ethyl-1,2,4-triazolederivatives tested for growth inhibitory activity against Bacillus subtilis, was performedusing the computer-assisted multiple regression procedure. Using the Hansch and FreeWilson approaches the activity contribution for either the aminomethyl/aminoethyl unitor the aromatic/heteroaromatic ring was determined from the correlation equation.

Keywords: QSAR/QSPR; N1-heteroarylamino/methyl/ethyl-1; 2; 4-triazole; physico- chemical parameters

Article Statistics

Click here to load and display the download statistics.

Cite This Article

MDPI and ACS Style

Dimova, V.; Ragenovic, K.C.; Kakurinov, V. QSAR of Some N¹-Aryl/Heteroarylaminomethyl/ethyl-1,2,4-Triazoles Part II: Antimicrobial Activity Against BacillusSubtilis. Int. J. Mol. Sci. 2006, 7, 119-129.

AMA Style

Dimova V., Ragenovic K.C., Kakurinov V. QSAR of Some N¹-Aryl/Heteroarylaminomethyl/ethyl-1,2,4-Triazoles Part II: Antimicrobial Activity Against BacillusSubtilis. International Journal of Molecular Sciences. 2006; 7(4):119-129.

Chicago/Turabian Style

Dimova, Vesna; Ragenovic, Katica C.; Kakurinov, Vladimir. 2006. "QSAR of Some N¹-Aryl/Heteroarylaminomethyl/ethyl-1,2,4-Triazoles Part II: Antimicrobial Activity Against BacillusSubtilis." Int. J. Mol. Sci. 7, no. 4: 119-129.

Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI Publishing, Basel, Switzerland RSS E-Mail Table of Contents Alert